3-Hydroxy-4,5(R)-Dimethyl-2(5H)-Furanone 以 乙醇 用作溶剂,化学反应生成葫芦巴内酯 参考文献:Distribution And Organoleptic Impact Of Sotolon Enantiomers In Dry White Wines 标题:Distribution And Organoleptic Impact Of Sotolon Enantiomers In Dry White Wines 摘要:The Enantiomers Of Sotolon,A Flavor Compound Typical Of Oxidized White Wines,Were Separated By Preparative HPLC To Determine Their Perception Thresholds And Distribution In Wines. The Enantiomeric Ratios Of Chiral Sotolon Were Evaluated In Several Dry White Wines Using Gas Chromatography And A Chiral Column (Beta-Cyclodextrin). Connected To A 2 M Precolumn (Bp20). The Perception Threshold Of (S)-Sotolon (0.8 Mu G/l) In Model Wine Solution Was 100 Times Lower Than That Of The (R) Form (89 Mu G/l),Indicating That (S)-Sotolon Contributes To The Characteristic Aroma Of Prematurely Aged Dry White Wines. Both Enantiomers; Are Detected In White Wines. Analysis Of Commercial Dry White Wines From Various Vintages And Origins Revealed Three Types Of Distribution Patterns: The Racemic Form,An Excess Of R,And An Excess Of S. The Proportions Found In These Wines May Be Partially Explained By The Slow Racemization Kinetics (20 Months) Of Optically Active Sotolon. Doi:10.1021/jf072337R
专利号:US-11534494-B2 优先权日:2011-12-21 标题 :Formulation and method of synthesis 发明人:DYRSTAD KNUT RICHARD; WICKSTROM TORILD; RAJANAYAGAM THANUSHAN; ROMOREN KRISTINE; RYAN OLAV 权利人:GE HEALTHCARE LTD 摘要:The present invention provides a novel method for the preparation of 18F-fluoride (18F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation of 18F-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.
专利号:WO-2013179196-A1 优先权日:2012-05-28 标 题:Process for the treatment of fermented vegetable-based beverages 发明人:TROTTA FRANCESCO; BIASIZZO MIRIAM; FERRUTI PAOLO; RANUCCI ELISABETTA 权利人:ESSECO S R L 摘要:A process of treatment of fermented beverages of vegetable origin, in particular wine, is disclosed, which provides the contact between the beverage and a polymer obtained by radical or sol-gel synthesis, selected from the group based on a-, p -, y-cyclodextrins and their derivatives and mixtures. This treatment removes from the fermented beverage molecules that harm its organoleptic propertes. According to a variant of the process, said polymers are synthetised according to the technique of the molecular imprinting. Advantageously, the process is implemented by packing a column, for example a chromatographic column, with polymer, for example in pellets, powder or bead, and by passing the beverage to be treated with a calculated flow rate in order to allow the beverage to stay sufficient time in the column to allow the said absorption. The process according to this invention can be utilised for stabilising the protein fractions in wines.
专利号:CA-2568954-A1 优先权日:2006-11-27 标题 :Synthesis of spirocyclic glucose-proline hybrids and methods of use
专利号:CN-101512004-A 优先权日:2006-07-19 标 题:Microbial Synthesis of D-1,2,4-Butanetriol
专利号:DE-69716426-T2 优先权日:1996-05-31 标 题:ENANTIOSELECTIVE SYNTHESIS OF AZETIDINONES BASED ON 3-HYDROXY GAMMA LACTONE
专利号:EP-0906278-B1 优先权日:1996-05-31 标 题:3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
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合成参考文献
参考文献:10.1007/s11033-011-0899-7 摘要:Qin JC, Zhang YM, Lang CY, Yao YH, Pan HY, Li X. Cloning and functional characterization of a caffeic acid O-methyltransferase from Trigonella foenum-graecum L. Mol Biol Rep. 2012 Feb;39(2):1601–8. doi: 10.1007/s11033-011-0899-7.