CAS: 1906-82-7; Ac-Gly-Oet

该化合物是一种有机化合物,其结构特征包括乙基组,乙酰胺组和乙酰基动物,其典型表现为无色的黄色淡液,有温和的气味;该化合物溶于乙醇和乙醚等有机溶剂,但因其缺水乙基类而在水中溶解性有限;乙酰乙胺乙酸酯因其在有机合成中的用途而闻名,特别是作为各种制药和农用化学品制作的中间体,在标准条件下具有中等稳定性,但在有强酸或碱的情况下可能进行水解.该化合物的再活性受乙酰氨基生物组的存在影响,该物质可参与各种化学反应,包括循环和消化.在处理该物质时,应当采取安全防范措施,因为它可能会对皮肤和眼睛产生刺激.总体而言,乙酰甲胺甲酸酯是一种多用途化合物,在化学合成中具有重大用途.

结构式图片

相似化合物

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合成工艺路线路线简述

    📜2-Acetamido-3-Ethoxy-3-Oxopropanoic Acid置于吡啶,Sodium Ethanolate体系中,化学反应生成乙酰甘氨酸乙酯
    参考文献:α-乙酰氨基乙酰乙酸乙酯的制备及一些反应.
    标题:α-乙酰氨基乙酰乙酸乙酯的制备及一些反应.
    摘要:
    Doi:10.1021/ja01183A081

    海关参考信息

    专利信息


    专利号:US-2005119332-A1
    优先权日:1998-03-12
    标 题 :Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
    发明人:JEPPESEN LONE; ANDERSEN HENRIK S; OLSEN OLE H; JUDGE LUKE M; HOLSWORTH DANIEL D; BAKIR FARID; AXE FRANK U; GE YU
    摘要:The present invention provides novel compounds of formula 1a, n nnovel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

    专利号:US-2002165398-A1
    优先权日:1998-03-12
    标题:Modulators of protein tyrosine phosphatases (PTPases)
    发明人:JEPPESEN LONE; ANDERSEN HENRIK SUNE; OLSEN OLE HVILSTED; JUDGE LUKE MILBURN; HOLSWORTH DANIEL DALE; BAKIR FARID; AXE FRANK URBAN; GE YU
    摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. n The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimers disease and schizophrenia, and infectious diseases.

    专利号:US-2621187-A
    优先权日:1950-10-06
    标题 :Synthesis of tryptophane and derivatives thereof
    发明人:JONES REUBEN G; KORNFELD EDMUND C
    权利人:LILLY CO ELI

    专利号:CN-105693619-A
    优先权日:2016-03-01
    标题:A kind of method of inorganic salt composite catalyst catalytic synthesis 1H-imidazole-4-formic acid

    专利号:CN-105646270-A
    优先权日:2015-12-22
    标题 :Synthesis method of imidazole carboxylate pharmaceutical intermediate ethyl acetamidoacetate

    专利号:CN-106431959-A
    优先权日:2015-12-22
    标 题 :Synthesis method of imidazole carboxylate drug intermediate ethyl acetamidoacetate

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

    合成参考文献


    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 149.
    摘要:Ipaktschi, J.; Saidi, M. R., Science of Synthesis Knowledge Updates, (2012) 4, 431.
    摘要:Li, X.; Song, Q., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 298.
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