📜3-丁炔-2-醇置于三甲基氯硅烷体系中,用60%的收率获得2-三甲基硅氧基-3-丁炔 参考文献:Novel Acetylenic Compounds Useful As Starting Materials For Preparing An 标题:Novel Acetylenic Compounds Useful As Starting Materials For Preparing An 摘要:新型乙炔化合物,可用作制备β-单萜酮的起始材料.其制备过程和用途.
专利号:US-4661641-A 优先权日:1983-06-09 标题 :Substituted alkynes useful as intermediates in the synthesis of carotenoids 发明人:LUKAC TEODOR; SOUKUP MILAN; WIDMER ERICH 权利人:HOFFMANN LA ROCHE 摘要:Compounds of the formula ##STR1## wherein n is either 0 or 1; R 1 and R 2 is hydrogen and the other is hydrogen, hydroxy, oxo group, a protected hydroxy or protected oxo group; R 3 is hydroxy oxo group, â•?CH--CH 2 --OH, â•?CH--CHO or one of the foregoing groups where the hydroxy or oxo functions are protected; R 4 is --CO--OR 6 , --CO--R 6 , --CO--NR 6 R 7 , --CO--Cl or --SO 2 --R 6 ; R 6 is saturated or aromatic hydrocarbon; and R 7 is saturated or aromatic hydrocarbon or hydrogen, n are converted by cleavage of R 4 OH into corresponding cycloalkenes and protecting groups, if present, are hydrolyzed. n The compounds obtained are valuable intermediates in carotenoid syntheses.