CAS: 122965-43-9; 3,7-Bis(Dimethylamino)Phenothiazin-5-Ium Chloride Xhydrate

该化合物是一种化学化合物,其结构复杂,包括一个苯并氮核心,在3和7个位置上以两个二甲基氨基组替代.该化合物一般是固体,以其充满活力的颜色而著称,通常与用作染料或生物应用有关.氯化离子的存在表明它是一种盐,而水合物形式表明它含有水分子,水合物结构中的水分子能够影响其溶性与稳定性.二甲基氨基组有助于其基本性和潜在反应,使其在化学和生物的各种环境中有用.此外,该化合物还可能显示出有趣的光物理特性,例如荧光,可以在成像或感感学应用中加以利用.其具体应用和行为可能因使用的环境而不同.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

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    专利信息


    专利号:US-2025296906-A1
    优先权日:2022-08-24
    标 题 :Method for preparing 4-hydroxy-2-methylene-butanal, 4-hydroxy-2-methyl-but-2-enal and esters thereof
    发明人:SCHAEFER BERND; SIEGEL WOLFGANG
    权利人:BASF SE
    摘要:The present invention relates to a method for preparing 4-hydroxy-2-methylene-butanal, 4-hydroxy-2-methyl-but-2-enal and esters thereof of the formula (I.a) and (I.b) where R1 is as defined in the claims and the description, by subjecting isoprenol or an ester thereof to a photooxidation in the presence of a photosensitizer and an acylating agent. The invention relates moreover to certain hydroperoxides of the compounds (I.a) or (I.b), and to the use thereof as intermediates in the synthesis of compounds (I.a) and (I.b) or in the synthesis of retinol, stereoisomers and derivatives thereof.

    专利号:US-11878021-B2
    优先权日:2006-07-11
    标题 :Methods of synthesis and/or purification of diaminophenothiazinium compounds

    专利号:US-9987358-B2
    优先权日:2012-08-20
    标题:Nanostars and nanoconstructs for detection, imaging, and therapy
    发明人:VO-DINH TUAN; Yuan Hsiangkuo; FALES ANDREW; KHOURY CHRISTOPHER
    权利人:UNIV DUKE
    摘要:A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.

    专利号:US-2021322435-A1
    优先权日:2006-07-11
    标题 :Methods of synthesis and/or purification of diaminophenothiazinium compounds

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Fenn Am, Et, Al. Methylene Blue Attenuates Traumatic Brain Injury-Associated Neuroinflammation And Acute Depressive-Like Behavior In Mice. J Neurotrauma. 2015 Jan 15;32(2):127-38.
    [参考文献]: Hochgräfe K, Et, Al. Preventive Methylene Blue Treatment Preserves Cognition In Mice Expressing Full-Length Pro-Aggregant Human Tau. Acta Neuropathol Commun. 2015 May 10;3:25.
    [参考文献]: Klamer D, Et, Al. Phencyclidine-Induced Behaviour In Mice Prevented By Methylene Blue. Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):65-72.
    [参考文献]: Emilia Konowa, Et Al. Functionalization Of Organically Modified Silica With Gold Nanoparticles In The Presence Of Lignosulfonate. Int J Biol Macromol. 2016 Apr:85:74-81.

    合成参考文献


    参考文献:10.1007/s11418-011-0546-6
    摘要:Lee JK, Kang DG, Lee H. Vascular relaxation induced by aqueous extract of Lespedeza cuneata via the NO-cGMP pathway. Journal of Natural Medicines. 2011 May 24;66(1):17–24. doi: 10.1007/s11418-011-0546-6.
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