专利号:US-2025296906-A1 优先权日:2022-08-24 标 题 :Method for preparing 4-hydroxy-2-methylene-butanal, 4-hydroxy-2-methyl-but-2-enal and esters thereof 发明人:SCHAEFER BERND; SIEGEL WOLFGANG 权利人:BASF SE 摘要:The present invention relates to a method for preparing 4-hydroxy-2-methylene-butanal, 4-hydroxy-2-methyl-but-2-enal and esters thereof of the formula (I.a) and (I.b) where R1 is as defined in the claims and the description, by subjecting isoprenol or an ester thereof to a photooxidation in the presence of a photosensitizer and an acylating agent. The invention relates moreover to certain hydroperoxides of the compounds (I.a) or (I.b), and to the use thereof as intermediates in the synthesis of compounds (I.a) and (I.b) or in the synthesis of retinol, stereoisomers and derivatives thereof.
专利号:US-11878021-B2 优先权日:2006-07-11 标题 :Methods of synthesis and/or purification of diaminophenothiazinium compounds
专利号:US-9987358-B2 优先权日:2012-08-20 标题:Nanostars and nanoconstructs for detection, imaging, and therapy 发明人:VO-DINH TUAN; Yuan Hsiangkuo; FALES ANDREW; KHOURY CHRISTOPHER 权利人:UNIV DUKE 摘要:A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.
专利号:US-2021322435-A1 优先权日:2006-07-11 标题 :Methods of synthesis and/or purification of diaminophenothiazinium compounds
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合成参考文献
参考文献:10.1007/s11418-011-0546-6 摘要:Lee JK, Kang DG, Lee H. Vascular relaxation induced by aqueous extract of Lespedeza cuneata via the NO-cGMP pathway. Journal of Natural Medicines. 2011 May 24;66(1):17–24. doi: 10.1007/s11418-011-0546-6.