CAS: 115-46-8; Azacyclonol

相似化合物

461648-39-5 185066-37-9 38081-60-6

上下游产品

CAS号114399-88-1 α,α-diphenyl-1-... | CAS号96067-93-5 4-羟基二苯基甲基哌啶-1-羧酸苄酯 | CAS号108-20-3 异丙醚 | CAS号112818-77-6 ethyl 4-(hydrox... | CAS号108-86-1 溴苯 | CAS号24228-40-8 1-苄基-4-哌啶甲酸乙酯 | CAS号1126-09-6 异哌啶酸乙酯 | CAS号160809-38-1 N-CBZ-4-哌啶甲酸乙酯 | CAS号1620-30-0 二苯基(4-吡啶基)甲醇 | CAS号6071-92-7 (1-methylpiperi... | CAS号105955-84-8 4-[4-[hydroxy(d... | CAS号50706-57-5 4-二苯基亚甲基哌啶 | CAS号50679-08-8 特非那定 | CAS号19841-73-7 Piperidine,4-(d... | CAS号83799-24-0 非索芬那定 | CAS号154477-55-1 2-(4-(4-(4-(羟基二... | CAS号154825-96-4 2-(4-(1-羟基-4-(4... | CAS号169280-33-5 A,a-二甲基-4-[4-[4... | CAS号43076-30-8 特非那酮 | CAS号5704-22-3 N-(1,3-benzodio...

(1-甲基哌啶-4-基)-二苯基甲醇置于potassium Carbonate体系中,用 乙醇,氯仿 用作溶剂,化学反应 24.0H,反应生成α,α-二苯基-4-哌啶甲醇
参考文献:Synthesis And In Vitro Antiproliferative Activity Of Diphenyl(Sulphonylpiperidin-4-yl)Methanol Derivatives
标题:Synthesis And In Vitro Antiproliferative Activity Of Diphenyl(Sulphonylpiperidin-4-yl)Methanol Derivatives
摘要:A Series Of Novel Diphenyl(Piperidin-4-yl)Methanol Derivatives 10(A-N) Were Synthesized And Characterized By H-1 NMR,Lc/ms,Ftir,And Elemental Analyses. All The Synthesized Compounds Were Evaluated For Cell Proliferation By Mtt Assay. The Antiproliferative Effects Of The Synthesized Compounds Were Tested Against Viable Human Skin Fibroblast Cell Line And Carcinoma Cell Lines,Namely Hela Cells,Ht-29 Cells,Mcf-7 Cells,And Hepg-2 Cells In Comparing The Positive And Negative Control. Among The Synthesized Compounds,(10B) And (10G) Have Been Identified As Potent Antiproliferative Agents.
Doi:10.1007/s00044-009-9186-8

专利信息

专利号:US-6147217-A
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives
发明人：SENANAYAKE CHRIS HUGH; FANG QUN KEVIN; WILKINSON SCOTT HAROLD
权利人:SEPRACOR INC
摘要:Processes for preparing compounds having the general formula: ##STR1## wherein R 1a is protected carboxy, carboxy, hydroxymethyl, protected hydroxymethyl, or methyl are disclosed. Processes of the invention begin with a starting material of the general formula IV ##STR2## wherein R 1 and R 2 are as defined in the specification.

专利号:US-7749985-B2
优先权日:2006-09-15
标 题 :Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
发明人：GALLOP MARK A; XU FENG; PHAN THU; DILIP USHA; PENG GE
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of making acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of using acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, and pharmaceutical compositions comprising acyloxyalkyl carbamate prodrugs 3-aminopropylphosphinic acid and analogs thereof for treating diseases or disorders such as mild cognitive impairment, cognitive impairment associated with Alzheimer's disease Alzheimer's disease, depression, anxiety, and epilepsy are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, which are suitable for oral administration and sustained release oral dosage forms are also disclosed.

专利号:ES-2421810-B1
优先权日:2012-03-02
标 题 :USEFUL INTERMEDIATES FOR THE SYNTHESIS OF FEXOFENADINE, PROCEDURES FOR ITS PREPARATION AND FOR THE PREPARATION OF FEXOFENADINE

专利号:US-2013237709-A1
优先权日:2012-03-02
标题 :Intermediates useful for the synthesis of fexofenadine, processes for their preparation and for the preparation of fexofenadine

专利号:US-5925761-A
优先权日:1997-02-04
标 题:Synthesis of terfenadine and derivatives

专利号:JP-4330179-B2
优先权日:1997-02-04
标 题 :Synthesis of terfenadine and derivatives.