专利号:WO-2024260915-A1 优先权日:2023-06-19 标题:Dynamic covalent chemistry of spiropyrans for synthesis of photoswitchable photoinitiators and uses thereof 发明人:GARMSHAUSEN YVES 权利人:XOLO GMBH 摘要:The present invention relates to spiropyrans and process for the manufacture of them. In particular, a method is provided to exchange the indole and salicylaldehyde part of a spiropyran in a reversible reaction. The method is used for the synthesis of dual color photoinitiators with specific substituents and substitution patterns, which result in improved dual color volumetric printing (xolography). Furthermore, a process for locally polymerizing a starting material by dual color photopolymerization is disclosed.
专利号:US-12172946-B2 优先权日:2019-01-07 标题:Compound containing diphenylmethane structure and use thereof 发明人:LIANG WEIZHOU; ZHENG QINGQUAN; TANG QI 权利人:GUANGZHOU TROJAN PHARMATEC LTD 摘要:A structure of the compound containing a diphenylmethane structure of the present invention is represented by General Formula (1). The compound containing a diphenylmethane structure of the present invention contains a hydroxyl group, an amino group, a substituted amino group, and an active group, and can be used as an amino acid or peptide C-terminal protection reagent. A peptide synthesis reaction using this protection carrier has a fast reaction speed and a high reagent utilization rate in a suitable solvent system; post-treatment is carried out by means of simple liquid-liquid extraction separation, i.e. effective purification can be carried out, and finally, a product with a high purity can be obtained; and during a synthesis process, the change in solubility is small and an operation process has a strong universality, and therefore, the present method can be developed into a universal production method.
专利号:US-4728542-A 优先权日:1985-06-19 标 题 :Ionically modified pur spreading pastes and their use 发明人:NACHTKAMP KLAUS; THOMA WILHELM; PEDAIN JOSEF; SCHROEER WALTER; LANGEL ROLF; NOLL KLAUS 权利人:BAYER AG 摘要:The present invention is directed to the preparation of optionally pigmented spreading paste based on multiphase mixtures of ionically-modified polyurethanes and/or polyurethane ureas which are prepared from special synthesis components based on silicone resins, aromatic hydroxypolyethers, aromatichydroxy polyesters, and perfluorocarbon resins, the multiphase mixtures additionally containing water and organic solvents for the polyurethanes and/or polyurethane ureas. The present invention is also directed to the preparation of these optionally pigmented spreading pastes and to their use for the production of coatings permeable to water vapor on fabric or leather substrates by the direct or transfer method using the technique of evaporation.
专利号:US-10988466-B2 优先权日:2017-03-23 标题:Heterocyclic derivatives useful as SHP2 inhibitors 发明人:MA CUNBO; GAO PANLIANG; HU SHAOJING; XU ZILONG; HAN HUIFENG; WU XINPING; KANG DI 权利人:JACOBIO PHARMACEUTICALS CO LTD 摘要:This invention relates to certain novel pyrazine derivatives (Formula I) as SHP2 inhibitors which is shown as formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention is directed to fused heterocyclic group derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder.