CAS: 927679-54-7; Rel-(1R,5S,6R)-3-(Tert-Butoxycarbonyl)-3-Azabicyclo[3.1.0]Hexane-6-Carboxylic Acid
化学文摘社编号927679-54-7,便于在化学数据库中识别; 总的来说,该物质可能具有有趣的药理学特性,因此可以作为在医药化学和相关领域进行进一步研究的候选体系; 其结构复杂性和功能组表明其在药物开发或作为各种化学反应的合成中间体中的潜在应用.
- 英文名称Rel-(1R,5S,6R)-3-(Tert-Butoxycarbonyl)-3-Azabicyclo[3.1.0]Hexane-6-Carboxylic Acid
- 中文名称外-3-[(叔丁氧基)羰基]-3-氮杂双环[3.1.0]己烷-6-羧酸
- IUPAC名称(1R,5S,6r)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
- 其它别名外-3-[(叔-丁氧基)羰基]-3-氮杂二环[3.1.0]己烷-6-羧酸; Exo-3-Boc-3-Azabicyclo[3.1.0]Hexane-6-Carboxylic Acid
- CAS编号927679-54-7
- MFCD编号:MFCD12198680
- EINECS号:810-736-1
- 分子式:C11H17NO4分子量:227.26
- 产品CID: 1966120
- 产品分类有机原料→分子砌块→桥环类化合物→其它桥环类化合物
相似化合物
1401464-07-0 1119512-39-8 134575-15-8物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别急性毒性 类别4(经口)
急性毒性 类别4(吸入)
急性毒性 类别4(经皮)
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
严重眼刺激 类别2A - 警示词Warning(警告)
- 危险描述H302 |吞咽有害.
H332 |吸入有害.
H312 |皮肤接触有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
欧盟法规
ECHA物质C&L通报合成工艺路线路线简述
- 134575-37-4 = 927679-54-7
反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Ethanol,Water; 0 °C; 3 H,Rt
标题:Preparation Of Novel 6-Pyrazolylamido-3-Substituted Azabicyclo[3.1.0]Hexane Compounds As Calcium Channel Inhibitors
参考文献:United States]
134575-37-4 = 927679-54-7
反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Methanol,Water; 12 H,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5
标题:Quinazoline Derivatives As Tyrosine Kinase Inhibitor,Compositions,Methods Of Making Them And Their Use
参考文献:World Intellectual Property Organization]
134575-37-4 = 927679-54-7
反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Ethanol,Water; 0 °C; 3 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
标题:Synthesis And Evaluation Of 6-Pyrazoylamido-3N-Substituted Azabicyclo[3,1,0]Hexane Derivatives As T-Type Calcium Channel Inhibitors For Treatment Of Neuropathic Pain
作者:Kim,Jung Hyun; Nam,Ghilsoo
参考文献:Bioorganic & Medicinal Chemistry 日期:2016 卷标:24(21) 页码:5028-5035]
419572-18-2 = 927679-54-7
反应条件:1.1 Reagents: Pyridinium Chlorochromate Solvents: Dimethylformamide; 16 H1.2 Reagents: Water
标题:Preparation Of Azabicyclohexane Derivatives For Treating Diabetes Mellitus And Metabolic Disorders
参考文献:China]
= 927679-54-7 [标题:Reaction Conditions
标题:Preparation Of Pyridine-3-Sulfonamide Derivatives As Amine Oxidase Copper Containing 3 (Aoc3) Inhibitors And Pharmaceutical Compositions And Uses Thereof
参考文献:World Intellectual Property Organization
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11834435-B2
优先权日:2021-09-14
标 题:SSTR4 agonist salts
发明人：COATES DAVID ANDREW; REMICK DAVID MICHAEL
权利人:LILLY CO ELI
摘要:The present invention relates to specific salts of (1S,5R)-(1α,5α,6α)-N-[1,1-dimethyl-2-[(3-methyl-2-pyridyl)oxy]ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide, to pharmaceutical compositions comprising said salts, to methods of using said salts to treat physiological disorders, and to intermediates useful in the synthesis of the salts.
