CAS: 69385-30-4; 2,6-Difluorobenzylamine

上下游产品

CAS号697-73-4 2,6-二氟氯苄 | CAS号19064-16-5 2,6-二氟苯甲醛肟 | CAS号133563-41-4 N-[(2,6-difluor... | CAS号352303-66-3 5-BROMO-1-(2,6-... | CAS号352303-65-2 1-(2,6-DIFLUORO... | CAS号17751-24-5 (2,6-Difluoro-b...

2,6-二氟苯腈置于ammonium Hydroxide,氢气体系中,用 水,异丙醇 作为反应溶剂,60.0~80.0 °C,1.0 Mpa 条件下,以90%的收率获得产物2,6-二氟苄胺
参考文献: Process For Preparation Of Halogenated Benzylamine And Intermediates Therof[fr] Procédé De Préparation De Benzylamine Halogénée Et De Ses Intermédiaires
标题: Process For Preparation Of Halogenated Benzylamine And Intermediates Therof[fr] Procédé De Préparation De Benzylamine Halogénée Et De Ses Intermédiaires
摘要:本发明提供了一种改进的工艺,用于从卤代苯腈制备具有化学式i的卤代苄胺,式中x1选自氢,氯或氟的组,要求至少有一个x1为氯或氟.

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-9670145-B2
优先权日:2014-03-31
标题:Process for preparing 1,1-disubstituted ethylene monomers
发明人：TCHAPLINSKI VLADIMIR; GHERARDI STEFANO; DE LA FUENTE MOLINA VERÓNICA
权利人:AFINITICA TECH S L
摘要:The present invention relates to a process for preparing 1,1-disubstituted ethylene monomers having general formula (I) from a compound of general formula (II) and an active methylene compound of general formula (III) using a catalytic amount of an ammonium or iminium a salt in homogeneous phase or supported on a solid substrate. Said process allows the direct synthesis of the monomers and finds application in the preparation of a wide variety of monomers. The products obtained are reactive monomers of high purity which find application in the field of fast curing adhesives.

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-5874443-A
优先权日:1995-10-19
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

专利号:WO-0050406-A1
优先权日:1999-02-22
标 题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAEL
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compouds.

专利号:WO-9931506-A1
优先权日:1997-12-18
标题 :Parallel solution phase synthesis of lactams