CAS: 538-03-4; 2-Amino-4-Arsorosophenol,Hydrochloride

专利信息

专利号:US-7807349-B2
优先权日:2002-11-29
标 题 :Protein synthesis monitoring (PSM)
发明人：SMILANSKY ZEEV
权利人:ANIMA CELL METROLOGY
摘要:A method and a device are disclosed for monitoring the synthesis of proteins by the ribosome in real time, in vivo as well as in in-vitro. The ribosome is engineered to carry a donor fluorophore, and tRNA and/or amino acids and/or some other part of the ribosome are either engineered to carry acceptor fluorophores or else their natural fluorescent properties are utilized as acceptors. As the ribosomes mechanism processed the mRNA and tRNA molecules and synthesizes a polypeptide chain, a light source illuminates the ribosome, exciting the donor fluorophores and thereby the acceptor fluorophores whenever these are in sufficient proximity to a donor. The resulting signals are detected and used as a key for real-time database searching and identification of the protein being synthesized. The resulting data can be tabulated and interpreted in different ways. FIG. ( 1 ) describes the properties of a FRET pair and the dependence of FRET on pair distance.

专利号:US-8442773-B2
优先权日:2002-11-29
标题:Protein synthesis monitoring (PSM)
发明人：SMILANSKY ZEEV
权利人:SMILANSKY ZEEV; ANIMA CELL METROLOGY
摘要:A method and a device are disclosed for monitoring the synthesis of proteins by the ribosome, wherein the ribosome is bound to a first label, for example a donor fluorophore, and a tRNA and/or amino acid are is bound to a second label, for example an acceptor fluorophore, wherein the first and second labels together from a FRET pair. As the ribosome mechanism processes the mRNA and tRNA molecules and synthesizes a polypeptide chain, a light source illuminates the ribosome, exciting the donor fluorophores and thereby the acceptor fluorophores whenever these are in sufficient proximity to a donor. The resulting signals are detected and used as a key for database searching and identification of the protein being synthesized.

专利号:CN-101636387-A
优先权日:2006-12-21
标题 :Process for the synthesis of diaminopyridines from glutarimidines

专利号:CN-101550236-B
优先权日:2008-03-07
标 题 :Synthesis of polyimide (PI) from polycarbodiimide and dianhydride via continuous self-repetitive reaction (SSRR)

专利号:CN-101550236-A
优先权日:2008-03-07
标题:Synthesis of polyimide (PI) from polycarbodiimide and dianhydride via continuous self-repetitive reaction (SSRR)

专利号:CN-1082062-C
优先权日:1998-12-28
标 题:Synthesis of foamed thermoplastic hard polyurethane plastic