CAS: 50606-31-0; Methyl Piperazine-1-Carboxylate

相似化合物

57260-70-5 57260-71-6 31166-44-6

上下游产品

CAS号219509-79-2 4-甲基哌嗪-1,4-二羧酸-1-叔丁酯 | CAS号110-85-0 哌嗪 | CAS号79-22-1 氯甲酸甲酯 | CAS号17175-16-5 甲基(4-硝基苯基)碳酸酯 | CAS号873697-71-3 4-[[2-氟-3-[N'-(... | CAS号7560-85-2 methyl 4-methyl...

1-哌嗪羧酸甲酯盐酸盐置于potassium Hydroxide体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,以14.5 G的收率获得产物哌嗪-1-羧酸甲酯
参考文献: Alternate Processes For The Preparation Of Omecamtiv Mecarbil[fr] Nouveaux Procédés Destinés à La Préparation De L'Omécamtiv Mécarbil
标题: Alternate Processes For The Preparation Of Omecamtiv Mecarbil[fr] Nouveaux Procédés Destinés à La Préparation De L'Omécamtiv Mécarbil
摘要:本申请的方面涉及制备omecamtiv Mecarbil及其盐的过程.具体方面涉及新型尿素中间体,其制备过程及其在制备omecamtiv Mecarbil及其盐中的应用.改进的omecamtiv Mecarbil制备过程具有工业可行性.

专利信息

专利号:US-11702380-B2
优先权日:2021-03-10
标 题:Synthesis of omecamtiv mecarbil
发明人：CAILLE SEBASTIEN; MURRAY JAMES; QUASDORF KYLE; NGUYEN HANNAH; SILVA ELIPE MARIA VICTORIA; ERICSON ARI ELIZABETH
权利人:AMGEN INC
摘要:Provided herein are synthetic methods for the preparation of intermediates that are utilized in the synthesis of omecamtiv mecarbil dihydrochloride.

专利号:US-12269811-B2
优先权日:2017-06-30
标 题:Synthesis of omecamtiv mecarbil
发明人：CAILLE SEBASTIEN; QUASDORF KYLE; ROOSEN PHILIPP C; SHI XIANQING; COSBIE ANDREW; WANG FANG; WU ZUFAN; NEERGUNDA ARCHANA; QUAN BIN PETER; GUAN LIANXIU
权利人:AMGEN INC
摘要:Provided herein is a synthesis for omecamtiv mecarbil dihydrochloride hydrate and various intermediates. (1)

专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人：BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

专利号:US-2023373955-A1
优先权日:2017-06-30
标 题:Synthesis of omecamtiv mecarbil

专利号:US-2022298099-A1
优先权日:2021-03-10
标题:Synthesis of omecamtiv mecarbil

专利号:TW-202300479-A
优先权日:2021-03-10
标 题:Synthesis of omecamtiv mecarbil