CAS: 21684-59-3; Ethyl 6-Methylnicotinate

该化合物是一种属于尼可辛酸衍生物类别的有机化合物,其特点是具有尼可辛化合物特征的环,代之以乙基酯组和在环的6位置的甲基组.该化合物一般没有颜色,可粉黄黄色液体,有香味,在乙醇和乙醚等有机溶剂中可溶解,但在水中溶解性有限.乙酰6-甲基硝基酯因其在制药和农用化学领域的潜在用途而闻名,特别是作为各种生物活性化合物合成的建筑块.此外,该化合物还可能展示生物活动,包括抗微生物和抗炎特性,尽管具体的生物影响可能因浓度和配方而不同.与许多有机化合物一样,由于潜在的毒性或刺激效应,应当观测适当的处理和安全防范措施.

结构式图片

相似化合物

3222-47-7 34107-46-5 53014-84-9

上下游产品

CAS号80658-26-0 (E)-N-methyl-N-... | CAS号623-47-2 丙炔酸乙酯 | CAS号3222-47-7 6-甲基烟酸 | CAS号64-17-5 乙醇 | CAS号78-94-4 丁烯酮 | CAS号3222-48-8 5-氰基-2-甲基吡啶 | CAS号110287-76-8 6-甲基哌啶-3-羧酸乙酯 | CAS号3430-13-5 5-溴-2-甲基吡啶 | CAS号3222-48-8 5-氰基-2-甲基吡啶 | CAS号3222-47-7 6-甲基烟酸 | CAS号34107-46-5 6-甲基-3-甲醇吡啶 | CAS号30766-11-1 5-溴-2-羧基吡啶 | CAS号53014-84-9 5-甲酰基-2-甲基吡啶 | CAS号21683-58-9 ethyl 3-(2-meth... | CAS号197079-25-7 6-甲基吡啶-3-碳酰肼 | CAS号36357-38-7 5-乙酰基-2-甲基嘧啶

合成工艺路线路线简述

  • 合成目标产物 Ethyl 6-Methylpyridine-3-Carboxylate 主要起始原料 2-Methyl-5-Vinylpyridine
  • (文献来源)合成步骤主要原料 2-Methyl-5-Vinylpyridine
📜Ethyl 2,4-Dihydroxy-6-Methylnicotinate置于乙醇,Potassium Acetate,钯,三氯氧磷体系中,化学反应生成6-甲基吡啶-3-甲酸乙酯
参考文献:Kooyman; Wibaut,Recueil Des Travaux Chimiques Des Pays-Bas,1946,Vol. 65,P. 10,13
标题:Kooyman; Wibaut,Recueil Des Travaux Chimiques Des Pays-Bas,1946,Vol. 65,P. 10,13

海关参考信息

专利信息


专利号:US-5322852-A
优先权日:1992-02-17
标 题:Aminooxy piperidines as ornithine decarboxylase inhibitors
发明人:FREI JOERG; STANEK JAROSLAV
权利人:CIBA GEIGY CORP
摘要:The invention relates to compounds of formula I (I) wherein either R1 is a radical of formula Ia, -(CH2)n-O-NH2(Ia) in which n is 0 or 1, is hydrogen and R2 is a radical of formula Ib, -(CH2)p-O-NH2(Ib) in which p is 1 or 2, and wherein R is C1-C2alkyl which is attached to one carbon atom of the central piperidine ring system, but not to the same carbon atom as R1 of formula Ia or as R2 of formula Ib; and m is 1 or 2, and salts thereof. The invention further relates to the preparation of these compounds, to intermediates obtained during their synthesis, to pharmaceutical compositions which contain them, and to the use of said compounds for the therapeutic treatment of the human or animal body and for the preparation of pharmaceutical compositions. The compounds of formula I are inhibitors of ornithin decarboxylase.

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Spitzner, D., Science of Synthesis Knowledge Updates, (2016) 1, 102.
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