CAS: 151864-81-2; Ethyl 4-(3-Oxopropyl)Benzoate

相似化合物

38628-51-2 151937-09-6 34961-64-3

上下游产品

Ethyl 4-bromobenzoate allyl alcohol 4-iodobenzoic acid ethyl ester acrylaldehyde diethyl acetal Ethyl 4-(4-hydroxy-3-oxobutyl)benzoate 4-(3-hydroxy-4-nitrobutyl)benzoic acid ethyl ester cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester 2-amino-5-(4'-ethoxycarbonyl-benzyl)thiophene-3-carboxylic acid ethyl ester

📜对碘苯甲酸乙酯置于palladium Diacetate 四丁基溴化铵,碳酸氢钠体系中,用 乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,以13.3 G (98%)的收率获得对乙氧基甲酰苯丙醛
参考文献:Us6066732
标题:Us6066732

专利信息

专利号:US-7259277-B2
优先权日:2003-07-25
标题 :Advanced route for the synthesis of cPLA2 inhibitors
发明人：WU YANZHONG; RAVEENDRATH PANOLIL
权利人:WYETH CORP
摘要:A process for making a compound of formula (I) n nin which process the compound HC≡C—(CH 2 ) n —NH 2 is reacted with the compound R 1 —SO 2 Cl to produce an intermediate compound, which intermediate compound is then reacted with the compound of formulan n nto produce the compound of formula (I), and compounds produced by the process of this invention. The terms R 1 , R 2 , R 3 , R 4 and n have the definitions set forth in the specification.

专利号:US-7582771-B2
优先权日:2003-09-03
标题:Process for the synthesis of cPLA2 inhibitors
发明人：DEHNHARDT CHRISTOPH M; MEGATI SREENIVASULU; MICHALAK RONALD S; RAVEENDRANATH PANOLIL; REN JIANXIN; WU CHARLES C; WU YANGZHONG
权利人:WYETH CORP
摘要:A process for making the compound of formula (I) n nwherein Ac represents acetate; X represents O or CH 2 ; Y represents C 1 -C 6 alkyl; and Z is selected from the group consisting of H, halogen, CN, CHO, CF 3 , OCF 3 , OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 thioalkyl, NH 2 , N(C 1 -C 6 alkyl) 2 , NH(C 1 -C 6 alkyl), NC(O)—(C 1 C 6 alkyl), and NO 2 . In his process, a compound of formula (II)n n nis reacted with hydrazine to form a primary alkylamine, and then the primary alkylamine is reacted with acetic anhydride, to produce the compound of formula (I).

专利号:US-7342119-B2
优先权日:2003-09-30
标题 :Process for the synthesis of a CPLA2 inhibitor
发明人：DEHNHARDT CHRISTOPH M; MEGATI SREENIVASULU; MICHALAK RONALD S; RAVEENDRANATH PANOLIL
权利人:WYETH CORP
摘要:A process for making a substituted indole compound, including the steps of: reacting the compounds n nin a non-protic polar solvent in the presence of a catalyst to form the intermediate compoundn n nwherein Ph and X are as defined herein; and then,n nheating this intermediate compound in the solvent in the presence of the catalyst to form the substituted indole compoundn n nThe invention also includes compounds formed by this process.

专利号:US-2005049296-A1
优先权日:2003-09-03
标 题 :Process for the synthesis of cPLA2 inhibitors

专利号:US-2008177085-A1
优先权日:2003-09-30
标 题:Process for the Synthesis of a CPLA2 Inhibitor

专利号:US-2005070723-A1
优先权日:2003-09-30
标 题 :Process for the synthesis of a CPLA2 inhibitor