CAS: 96-42-4; 3-Pyrrolidinone

该化合物是一个环状的环状沉积物,其特点是五人环状,内含氮原子和碳基组;在室温下,无色状黄色液体,呈现出温和,舒适的气味;该化合物溶于水和有机溶剂,可溶于水和有机溶剂,在各种应用中具有多种特性;3-Pyrroldinone因其作为溶剂和药物,农用化学品和其他有机化合物合成中间体的作用而著称;其化学结构允许其参与各种反应,包括核细胞代用品和循环添加剂;此外,已对其在聚合物化学和增塑剂中的潜在用途进行了研究;安全数据表明,尽管它可能对接触健康造成一些风险,但适当的处理和安全措施可以减轻这些关切.

结构式图片

欧盟法规

C&L通报

上下游产品

ethyl-3-oxo-1-pyrrolidinecarboxylate 4-ethoxycarbonyl-1-phenylpyrrolidine-3-one pyrrolidin-3-ol benzyl 3-oxopyrrolidine-1-carboxylate 5H9N3C5H9N3 3-[(4-fluorophenyl)amino]pyrrolidine (2S,4S)-2-[(4-oxopyrrolidynyl)methyl]-4-tritylthio-1-(allyloxycarbonyl)pyrrolidine 2-methoxy-1-pyrroline

合成工艺路线路线简述

    📜Ethyl 1-Phenyl-4-Oxo-3-Pyrrolidinecarboxylate 反应生成 3-吡咯烷酮
    参考文献:Kuhn; Osswald,Angewandte Chemie,1957,Vol. 69,P. 60
    标题:Kuhn; Osswald,Angewandte Chemie,1957,Vol. 69,P. 60

    海关参考信息

    专利信息


    专利号:US-9765027-B2
    优先权日:2014-08-22
    标题 :Substituted 1-arylethyl-4-acylaminopiperidine derivatives as opioid/alpha-adrenoreceptor modulators and method of their preparation
    发明人:VARDANYAN RUBEN S; HRUBY VICTOR J
    权利人:THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZAONA; UNIV ARIZONA
    摘要:The invention provides compounds that bind with high affinities to the μ-, δ- and κ-opioid receptors and α 2 -adrenoreceptor. In addition to providing these compounds with novel pharmacological binding properties, the invention also describes detailed novel methods for the preparation of representative compounds and a scheme for the synthesis of related compounds that bind to the opioid receptors and/or α 2 -adrenoreceptor.

    专利号:US-8728750-B2
    优先权日:2006-09-06
    标 题 :Process for preparation of optically active N-protected 3-aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
    发明人:ROBINS KAREN; BORNSCHEUER UWE; HÖHNE MATTHIAS
    权利人:ROBINS KAREN; BORNSCHEUER UWE; HÖHNE MATTHIAS; LONZA AG
    摘要:The present invention relates to the production of optically active amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products.

    专利号:US-2025163076-A1
    优先权日:2022-02-18
    标 题 :Synthesis of bruton's tyrosine kinase inhibitors
    发明人:TRAN NGOC DUC; XIOURAS CHRISTOS; CLEATOR EDWARD; MATON WILLIAM MARC; RAMMELOO THOMAS JOACHIM LANDEWALD; FERNANDES PHILIPPE; BONGARTZ JEAN-PIERRE A; CAO DUY CHI TRUNG; HORWITZ MATTHEW ALLAN; JUSSEAU XAVIER JEAN-MARIE; LEMAIRE SÉBASTIEN FRANCOIS-EMMANUEL; SCHWEITZER-CHAPUT BERTRAND
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The present disclosure is directed to methods of synthesizing a compound of Formula (I), where the R groups are defined herein, and to methods of synthesizing a compound of Formula (II). Some aspects of the present disclosure is directed to converting the compound of Formula (II) into its P form.

    专利号:US-5567830-A
    优先权日:1994-02-14
    标题 :Process for synthesis of acetylenic carbinols
    发明人:UPASANI RAVINDRA B
    权利人:COCENSYS INC
    摘要:A method for the preparation of an acetylenic alcohol by reaction of 1,2-dibromoethylene with an alkyl, aryl an heteroaryl lithium in an inert solvent, followed by reaction with a carbonyl-containing compound to give an acetylenic alcohol is disclosed.

    专利号:US-8399502-B2
    优先权日:2008-09-17
    标 题 :Analogs of indole-3-carbinol and their use as agents against infection
    发明人:JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN
    权利人:JONG LING; JIANG FAMING; LI GAOQUAN; MORTELMANS KRISTIEN; STANFORD RES INST INT
    摘要:Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2′-diindolylmethane, 2′,3-diindolylmethane, and 3,3′-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.

    专利号:US-9551018-B2
    优先权日:2006-02-13
    标 题 :Process for the preparation of optically active chiral amines
    发明人:ROBINS KAREN; SCHEUER UWE; HOHNE MATTHIAS
    权利人:LONZA AG
    摘要:The present invention relates to the production of optically pure secondary amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Simon, R. C.; Busto, E.; Fischereder, E.-M.; Fuchs, C. S.; Pressnitz, D.; Richter, N.; Kroutil, W., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 413.
    摘要:DiRocco, D. A.; Schultz, D. M., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 621.
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