CAS: 68449-30-9; 5-Bromo-3,4-Dihydronaphthalen-1(2H)-One

上下游产品

3,4-二氢-1(2H)-萘酮 3,4-Dihydronaphthalene-1(2H)-One 529-34-0

邻溴氰苄置于氢氧化钾,Lithium Aluminium Tetrahydride,三氯化铝,氯化亚砜,硫酸,氢溴酸,Sodium Ethanolate体系中,用 二硫化碳,乙醚,乙醇,水 作为反应溶剂,化学反应 24.75H,反应生成 5-溴-1-四氢萘酮
参考文献:Synthesis Of Biological Markers In Fossil Fuels. 2. Synthesis And Carbon-13 NMR Studies Of Substituted Indans And Tetralins
标题:Synthesis Of Biological Markers In Fossil Fuels. 2. Synthesis And Carbon-13 NMR Studies Of Substituted Indans And Tetralins
摘要:
DOI:10.1021/jo00196A024

专利信息

专利号:US-4777257-A
优先权日:1983-08-25
标题:Certain tetrahydronaphthyl or indanylcarboxylates and derivatives thereof which inhibit the synthesis of thromboxane
发明人：KANAO MUNEFUMI
权利人:DAIICHI SEIYAKU CO
摘要:Benzocycloalkane derivatives of the formula (I) ##STR1## wherein: Z represents a methylene group or an ethylene group, either one of R 1 and R 2 represents --(CH 2 ) m --COOR 3 and the other represents ##STR2## wherein R 3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an interger of 1 to 6 and m represents an interger of 0 to 5, and the physiologically acceptable salts thereof; having a strong and selective inhibition activity of thromboxane A 2 synthesis.

专利号:US-9394264-B2
优先权日:2009-11-13
标 题:Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA
权利人:RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-9481659-B2
优先权日:2011-05-13
标 题 :Selective heterocyclic sphingosine 1 phosphate receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD
权利人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD; CELGENE INT II SÀRL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-8148370-B2
优先权日:2008-03-21
标题 :Polysubstituted derivatives of 2-aryl-6-phenyl-imidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
发明人：DE PERETTI DANIELLE; EVANNO YANNICK
权利人:DE PERETTI DANIELLE; EVANNO YANNICK; SANOFI AVENTIS
摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

专利号:CA-2780433-C
优先权日:2009-11-13
标 题 :Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis

专利号:US-2015299150-A1
优先权日:2009-11-13
标题:Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis