CAS: 5341-61-7; Hydrazine Dihydrochloride

该化合物是一种稳定,可溶水的氢氰化物盐,通常用作有机合成的消毒剂和中间剂,其晶体形式确保了与自由的氢氰化物相比的连续反应和方便处理,而免费的氢氮具有高度挥发性和毒性.该化合物在生产异环,氢氮化物和其他含氮衍生物的制药和农业化学中特别受到重视.其高纯度和可预测的口服测量法使其适合精确的合成应用,包括催化剂系统和交叉反应.此外,在标准条件下,其稳定性降低了储存和处理风险,为许多实验室和工业工艺中的氢化氢提供了更安全的替代物.

结构式图片

相似化合物

13775-80-9 7335-65-1 10034-93-2

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    Triphosphorus Trinitride Hexahydrazide置于盐酸体系中,用 水 作为反应溶剂,化学反应生成 盐酸肼
    参考文献:Triphosphonitrilic Hexahydrazide
    标题:Triphosphonitrilic Hexahydrazide
    摘要:
    DOI:10.1021/ja01547A021

    专利信息


    专利号:US-10654862-B2
    优先权日:2015-03-18
    标题 :Methods for the chemical synthesis of pyrrole-linked bivalent compounds, and compositions thereof
    发明人:CRAN JOHN
    权利人:AVEKSHAN LLC
    摘要:The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.

    专利号:US-8586241-B2
    优先权日:2008-08-26
    标 题:Synthesis of LIFEPO4 under hydrothermal conditions
    发明人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH
    权利人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH; BASF SE
    摘要:The present invention relates to a process for the preparation of compounds of general Formula (I) L a-b M 1 b Fe 1-c M 2 c P d-e M 3 e O x (I), wherein Fe has the oxidation state +2 and M 1 , M 2 , M 3 , a, b, c, d, e and x are: M 1 : Na, K, Rb and/or Cs, M 2 : Mn, Mg, Al, Ca, Ti, Co, Ni, Cr, V, M 3 : Si, S, F a: 0.8-1.9, b: 0-0.3, c: 0-0.9, 15 d: 0.8-1.9, e: 0-0.5, x: 1.0-8, depending on the amount and oxidation state of Li, M 1 , M 2 , P, M 3 , wherein compounds of general Formula (I) are neutrally charged, comprising the following steps (A) providing a mixture comprising at least one lithium-comprising compound, at least one iron-comprising compound, in which iron has the oxidation state +3, and at least one M 1 -comprising compound, if present, and/or at least one M 2 -comprising compound, if present, and/or least one M 3 -comprising compound, if present, and at least one reducing agent which is oxidized to at least one compound comprising at least one phosphorous atom in oxidation state +5, and (B) heating the mixture obtained in step (A) at a temperature of 100 to 500° C. and at an autogeneous pressure to reduce Fe to oxidation state +2 and to obtain a compound of general Formula (I).

    专利号:US-9023523-B2
    优先权日:2009-03-17
    标题 :Synthesis of lithium-iron-phosphates under hydrothermal conditions
    发明人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH
    权利人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH; BASF SE
    摘要:The present invention relates to a process for the preparation of compounds of general formula (I) Li a-b M b 1 Fe 1-c M c 2 P d-e M e 3 O x , wherein Fe has the oxidation state +2 and M 1 , M 2 , M 3 , a, b, c, d, e and x are: M 1 : Na, K, Rb and/or Cs, M 2 : Mn, Mg, Al, Ca, Ti, Co, Ni, Cr, V, M 3 : Si, S, F a: 0.8-1.9, b: 0-0.3, c: 0-0.9, d: 0.8-1.9, e: 0-0.5, x: 1.0-8, depending on the amount and oxidation state of Li, M 1 , M 2 , P, M 3 , wherein compounds of general formula (I) are neutrally charged, comprising the following steps (A) providing a mixture comprising at least one lithium-comprising compound, at least one iron-comprising compound, in which iron has the oxidation state 0, and at least one M 1 -comprising compound, if present, and/or at least one M 2 -comprising compound, if present, and/or least one M 3 -comprising compound, if present, and at least one compound comprising at least one phosphorous atom in oxidation state +5, and (B) heating the mixture obtained in step (A) at a temperature of 100 to 500° C. and at an autogeneous pressure to obtain a compound of general formula (I).

    专利号:US-8981115-B2
    优先权日:2008-09-30
    标 题 :Process for the synthesis of halogenated cyclic compounds
    发明人:BRAUN MAX
    权利人:SOLVAY
    摘要:A process for the manufacture of a cyclic compound of formula (I) n n n n n n n n n n which comprises (a) adding an acid halide of formula R 1 —C (O)—X, to a vinyl ether of formula (II): CH 2 â•?CH—OR 2 , to produce an addition product, and (b) reacting the addition product with a compound of formula (III): Y-A-Z; wherein R 1 is a halogenated alkyl group; wherein X is fluorine, chlorine, or bromine; wherein R 2 is an alkyl group, an aralkyl group, or an aryl group; wherein Z and Y designate independently carbon or a heteroatom; and wherein A is a linking group between Z and Y comprising 0, 1, 2 or 3 atoms in the cycle.

    专利号:US-6593477-B1
    优先权日:2002-10-29
    标题:Synthesis of 3-acylaminopyrazoles
    发明人:ROMANET ROBERT F; FISCHER SUSAN M
    权利人:EASTMAN KODAK CO
    摘要:Disclosed is a process for forming an N-acylamino pyrazole comprising contacting a N-acyl-3-oxo-imino ether compound either with a salt of hydrazine in the presence of a base or with hydrazine.

    专利号:US-9156693-B2
    优先权日:2008-12-29
    标 题 :Synthesis of lithium-metal-phosphates under hydrothermal conditions
    发明人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH; SCHROEDLE SIMON
    权利人:BRAMNIK KIRILL; HIBST HARTMUT; LAMPERT JORDAN KEITH; SCHROEDLE SIMON; BASF SE
    摘要:The present invention relates to a process for the preparation of compounds of general formula (I) Li a-b M 1 b Q 1-c M 2 c P d-e M 3 e O x (l), wherein Q has the oxidation state +2 and M 1 , M 2 , M 3 ,a, b, c, d, e and x are: Q: Fe, Mn, Co, Ni, M 1 : Na, K, Rb and/or Cs, M 2 : Mg, Al, Ca, Ti, Co, Ni, Cr, V, Fe, Mn, wherein Q and M2 are different from each other,M 3 : Si, S, F a: 0.8-1.9, b: 0-0.3, c: 0-0.9, d: 0.8-1.9, e: 0-0.5, x: 1.0-8, depending on the amount and oxidation state of Li, M 1 , M 2 , P, M 3 , wherein compounds of general formula (I) are neutrally charged, comprising the following steps (A) providing a mixture comprising at least one lithium-comprising compound, at least one Q-comprising compound, in which Q has at least partially an oxidation state higher than +2, and at least one M 1 -comprising compound, if present, and/or at least one M 2 -comprising compound, if present, and/or least one M 3 -comprising compound, if present, and at least one reducing agent which is oxidized to at least one compound comprising at least one phosphorous atom in oxidation state +5, and (B) heating the mixture obtained in step (A) at a temperature of 100 to 500° C. and at an autogeneous pressure to reduce Q to oxidation state +2 and to obtain a compound of general formula (I).
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    主要参考文献

    [参考文献]: Alexandra Witze, Et Al. Green Fuels Blast Off. Nature. 2013 Aug 29;500(7464):509-10.
    [参考文献]: Alya M Al-Etaibi, Et Al. A Facile Synthesis Of New Monoazo Disperse Dyes Derived From 4-Hydroxyphenylazopyrazole-5-Amines: Evaluation Of Microwave Assisted Dyeing Behavior. Molecules. 2012 Nov 23;17(12):13891-909.
    [参考文献]: Chirantan Kar, Et Al. Nir- And Fret-Based Sensing Of Cu2+ And S2- In Physiological Conditions And In Live Cells. Inorg Chem. 2013 Jan 18;52(2):743-52.
    [参考文献]: Eunhee Lee, Et Al. Electrocatalytic Oxidation Of Hydrazine And Hydroxylamine By Graphene Oxide-Pd Nanoparticle-Modified Glassy Carbon Electrode. J Nanosci Nanotechnol. 2012 Dec;12(12):8886-92.
    [参考文献]: Mohammad Mahdi Doroodmand, Et Al. Discrete Fourier Transform As Applicable Technique In Electrochemical Detection Of Hydrazine Using Multi-Walled Carbon Nanotube/polyacrylonitrile Ceramic Fiber As Working Electrode. Mater Sci Eng C Mater Biol Appl. 2013 May 1;33(4):1969-74.

    合成参考文献


    摘要:Wicha, J., Science of Synthesis, (2009) 48, 121.
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