Tropin-Phenylglyoxylat,硼氢化钠 以80%的收率获得 参考文献:Koretskaya N. I.; Dombrovskaya K. I.; Shvarts G. Ya.; Mashkovskij M. D.,Xim.-Farmatsevt. Zh.,1977,11,Ho 7, 标题:Koretskaya N. I.; Dombrovskaya K. I.; Shvarts G. Ya.; Mashkovskij M. D.,Xim.-Farmatsevt. Zh.,1977,11,Ho 7,
专利号:US-5663345-A 优先权日:1992-12-31 标 题:Derivatives of benzoylecgonine, ecgonine and ecgonidine and methods for preparing and using same 发明人:SOMERS LOWELL M; WYNN JAMES E 权利人:ENTROPIN INC 摘要:The present invention relates to a novel class of benzoylecgonine, ecgonine and ecgonidine derivatives which are useful for preventing and treating immunoregulatory disorders, neuromuscular. disorders, joint disorders, connective tissue disorders, circulatory disorders and pain. The compounds of this invention are conveniently obtained by chemical synthesis. Accordingly, this invention also relates to methods for preparing the benzoylecgonine, ecgonine and ecgonidine derivatives and to pharmaceutical compositions containing these derivatives.
专利号:EP-1930323-A1 优先权日:2004-03-11 标 题:Biphenyl compounds useful in the synthesis of muscarinic receptor antagonists
专利号:EP-1930323-B1 优先权日:2004-03-11 标 题:Biphenyl compounds useful in the synthesis of muscarinic receptor antagonists
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.