CAS: 4171-83-9; (2-Nitrophenyl)(Phenyl)Sulfane

上下游产品

ethanol 2-nitrophenyl bromide sodium thiophenolate thiophenol 1-nitro-2-(phenylsulfinyl)benzene 1-nitro-2-(phenylsulfonyl)benzene 2-phenylsulfanyl-aniline 2-phenylsulfanyl-benzenesulfonic acid

邻硝基苯乙酮置于sodium Tetrahydroborate,1,10-菲罗啉,氧气,Potassium Carbonate,Copper(II) Sulfate体系中,用 甲醇,二甲基亚砜 作为反应溶剂,140.0 °C,500.01 Kpa 条件下,反应 12.17H,反应生成 2-硝基二苯硫醚
参考文献:通过芳基醇的c(芳基)-c键转化合成硫醚,芳烃和芳基苯并恶唑
标题:通过芳基醇的c(芳基)-c键转化合成硫醚,芳烃和芳基苯并恶唑
摘要:通过对c(芳基)-c(oh)键的选择性裂解和官能化将芳基醇转化为高价值的官能化芳族化合物至关重要,但到目前为止仍极具挑战性.在此,我们首次报道了通过氧化和脱羧功能化的合作来激活和官能化c(芳基)-c(oh)键的新颖且通用的策略.在基于铜的催化系统中,通过裂解c(芳基)-c(oh)键,可以使用多种芳基醇底物作为芳基化试剂,并以优异的收率有效地转化为相应的硫醚,芳烃和芳基化苯并恶唑产品ø 2作为氧化剂.这项研究为芳基醇的转化提供了一种新方法,并为从木质素等可再生原料生产高价官能化芳烃提供了新的机会,木质素在其键合中具有丰富的c(芳基)-C(oh)键.
DOI:10.1039/d0Sc01229G

专利信息

专利号:EP-1660469-B1
优先权日:2003-07-18
标题 :Process for the preparation of 11-(1-piperazinyl)dibenzo 'b, f! '1 ,4!-thiazepine, an intermediate in the synthesis of the antipsychotic drug quetiapine
发明人：KACZMAREK LUKASZ; BADOWSKA-ROSLONEK KATARZYNA; STOLARCZYK ELZBIETA; SZELEJEWSKI WIESLAW
权利人:HELM AG; INST FARMACEUTYCZNY
摘要:A process for the preparation of 11-(1-piperazinyl)dibenzo-[b, f ] [ 1, 4 ] thiazepine comprising reacting phenyl 2­(phenylthio) phenylcarbamate with piperazine and cyclizing the obtained N-[ (2 -phenylthio) phenyl ] -1 -piperazinylcarboxamide in a presence of cyclizing agent. 11-(1-piperazinyl)-dibenzo [b, f] [1, 4]thiazepine is itself, an intermediate in the synthesis of antipsychotic drug Quetiapine.

专利号:US-2024091731-A1
优先权日:2020-04-20
标题:Devices and methods for multiplexing chemical synthesis
发明人：ZHAO XIAOCHUAN; ZHANG XIAOLIN
权利人:LC SCIENCES
摘要:The present invention relates to the field of chemical synthesis. Specifically, the present invention relates to methods, materials, compositions, and devices for multiplexing chemical synthesis. In particular, the present invention provides novel methods, materials, compositions, and devices to synthesize plurality of chemical compounds, including but not limited to nucleic acids, peptides, saccharides, and phospholipids. Specifically, the present invention provides methods, materials, compositions, and devices to first form plurality of isolated wells on a solid substrate and then to carry out plurality of chemical reactions in the isolated wells, in parallel, and on the same substrate.

专利号:US-3426020-A
优先权日:1966-12-01
标题:Synthesis of 2-substituted phenothiazines
发明人：DONDZILA FRANK A; RESTIVO ALBERT R; YALE HARRY L
权利人:SQUIBB & SONS INC

专利号:US-4511729-A
优先权日:1982-04-30
标 题 :Nucleophilic substitution process
发明人：STAHLY G PATRICK; STAHLY BARBARA C
权利人:ETHYL CORP
摘要:Nitrophenoxy- or nitrophenylthiobenzeneacetic acid esters are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.

专利号:US-4502998-A
优先权日:1982-08-25
标题 :Nucleophilic substitution process
发明人：STAHLY BARBARA C; STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Nitrophenoxy- or phenylthiobenzeneacetonitriles are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-dinitrosubstituted acetonitrile in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.

专利号:WO-2005012274-A1
优先权日:2003-07-18
标 题 :Process for the preparation of 11-(1-piperazinyl)dibenzo `b, f! `1 ,4!-thiazepine, an intermediate in the synthesis of the antipsychotic drug quetiapine