CAS: 34675-84-8; 3-(4-((Trans-4-(Aminomethyl)Cyclohexane-1-Carbonyl)Oxy)Phenyl)Propanoic Acid

该化合物是一种属于磺酰胺类的化学化合物,主要被承认用于治疗某些医疗条件,特别是皮肤病学领域的医疗条件,催产素展示抗菌特性,使其对一系列细菌感染有效,其特征是其全氟辛烷磺酸功能组,这是其行动机制的组成部分,它通过干扰叶酸合成来抑制细菌生长.就物理特性而言,催产素通常是白到白的晶状粉,在水中可溶解,在标准条件下表现出稳定性,其药理学特征包括有利的安全幅度,尽管与所有药物一样,它可能具有潜在的副作用和反作用,在临床使用中应予以考虑.

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    专利信息


    专利号:WO-9824022-A1
    优先权日:1996-11-22
    标题:Method for incremental synthesis of a discrete technical system
    发明人:STEFFEN BERNHARD
    权利人:METAFRAME TECHNOLOGIES SOFTWAR; STEFFEN BERNHARD
    摘要:Disclosed is a method for knowledge-based incremental synthesis of a discrete technical system dependent upon a predetermined first configuration, wherein the first configuration represents an implemented consistent conflict-free causal structure. The first configuration comprises a predetermined knowledge base and a description of requirements controlling the synthesis, wherein a second configuration which fulfills the description of requirements is generated in the following steps: synthesis of a completed first intermediate causal structure that is not necessarily consistent or conflict-free, arising from the first configuration and the description of requirements by means of a fusion specification, and transformation of the first intermediate causal structure into a not necessarily conflict-free completed consistent second intermediate causal structure, and transformation of the completed second intermediate causal structure into a conflict-free consistent causal structure corresponding to the second configuration of the technical system by conflict resolution using conflict resolution conditions.

    专利号:EP-2260936-B1
    优先权日:2004-11-25
    标题:Method for specifically located synthesis of nucleic acids on solid carriers
    发明人:ELLINGER THOMAS; ERMANTRAUT EUGEN; HOLZHEY NANCY; PLENZ FRANK; SCHULZ TORSTEN; TUCHSCHEERER JENS; WEICHERDING DANIEL
    权利人:CLONDIAG GMBH
    摘要:Type-specific synthesis of bio-polymers of a defined sequence on pre-determined ranges of a solid carrier comprises gradual coupling of monomer and/or oligomer components (I); where, before the coupling step, at least a pre-determined area of the carrier are activated for coupling of (I) to activate the reactive groups; and the temporary group for protection are removed by addition of an activation reagent in aqueous solution, is new. Independent claims are also included for: (1) a procedure for the type-specific synthesis of biopolymers of a defined sequence on pre-determined ranges of solid carrier, comprising: (a) arranging a mask on the carrier (for coupling of (I) of the biopolymer, which is to be synthesized for controlling available reactive groups with protection groups to the carrier); (b) activating the reactive groups by removing the temporary protective groups at the ranges given by the mask, by adding the activation reagent in aqueous solution; (c) coupling (I) with activated reactive groups; and (d) repeating step (a) to (c), until the desired biopolymers is synthesized; (2) a micro array prepared by the process; and (3) a micro array with pre-determined ranges immobilized biopolymer probes, where the proportional portion P at biopolymers, which exhibits the desired number of monomer M, is given by the formula P = S-M (where S is an average step yield with the coupling of (I); and the density at pre-determined ranges is at least 1500 spots per cm 2>and the average step yield is 95 (preferably 98) %).

    专利号:EP-1546732-B1
    优先权日:2002-09-03
    标 题:Modulation of the synthesis of insulin
    发明人:WALTHER REINHARD
    权利人:UNIV ERNST MORITZ ARNDT
    摘要:The invention particularly relates to the use of substances, which modulate the activity of the proteins casein kinase II (CK II) and 14-3-3 epsilon and/or of the PcG protein EED or which influence the binding of the proteins casein kinase II (CK II) and 14-3-3 epsilon, of the PcG protein EED and/or of a fragment thereof with the protein pancreatic duodenal homeobox-1 (PDX-1) that plays a decisive roll in the glucose-induced biosynthesis of insulin, for influencing the synthesis of insulin or the provision of insulin.

    专利号:US-10040752-B2
    优先权日:2015-08-24
    标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
    发明人:MKRTCHYAN GNEL; YAO QINGWEI
    权利人:CODY LABORATORIES INC
    摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

    专利号:EP-1232226-B1
    优先权日:2000-09-08
    标题:Synthesis of nanoparticles
    发明人:HAUBOLD STEPHAN; HAASE MARKUS; RIWOTZKY CARSTEN; WELLER HORST; MEYSAMMY HEIKE; IBARRA FERNANDO
    权利人:NANOSOLUTIONS GMBH
    摘要:Production of inorganic nanoparticles that can be fluoresced consisting of a host material containing a dopant comprises using an organic solvent for liquid phase synthesis of the particles.

    专利号:WO-2019197122-A1
    优先权日:2018-04-10
    标 题:Process for treatment of at least one cell with a chemical synthesis product in a microarray
    发明人:BENZ MAXIMILIAN; LEVKIN PAVEL A; MOLLA MIJANUR R; ROSENFELD ALISA; BREHM MARIUS
    权利人:KARLSRUHER INST TECHNOLOGIE
    摘要:The present invention relates to a process for treatment of at least one cell with a chemical synthesis product in a microarray, a stacked microarray, a kit comprising at least one microarray and the use of a microarray for the chemical synthesis of a chemical synthesis product and for the treatment of at least one cell with the chemical synthesis product in a microarray.

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    主要参考文献


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    合成参考文献


    参考文献:10.1007/s10157-003-0254-y
    摘要:Kitamura H, Matsui I, Itoh N, Fujii T, Aizawa M, Yamamoto R, Okuno A, Okazaki Y, Fujita Y, Kuwayama Y, Imai E, Fujii M. Tranexamic acid-induced visual impairment in a hemodialysis patient. Clinical and Experimental Nephrology. 2003 Dec 01;7(4):311–4. doi: 10.1007/s10157-003-0254-y.
    参考文献:10.1007/bf02100147
    摘要:Fukumura D, Miura S, Kurose I, Higuchi H, Suzuki H, Ebinuma H, Han J, Watanabe N, Wakabayashi G, Kitajima M, Ishii H. IL-1 is an important mediator for microcirculatory changes in endotoxin-induced intestinal mucosal damage. Digestive Diseases and Sciences. 1996 Dec;41(12):2482–92. doi: 10.1007/bf02100147.
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