📜2-苯基丙酸,布洛芬,钠 反应生成布洛芬钠 参考文献:Process Of Resolving Phenylpropionic Acids Using 标题:Process Of Resolving Phenylpropionic Acids Using 摘要:一种生产制备含有苯丙酸的手性异构体的产品的方法,所述苯丙酸选自布洛芬和氟布洛芬,或其药用盐,该方法包括分离阶段,再结晶阶段,可选的解放阶段和可选的盐制备阶段.将苯丙酸的基本混合物与α-甲基苯乙胺的手性异构体以特定比例接触,以制备手性富集的产品.
专利号:US-4282252-A 优先权日:1980-05-15 标 题 :Method of increasing coronary blood flow with ibuprofen 发明人:LEFER ALLAN M 权利人:UNIV JEFFERSON 摘要:Novel treatments are disclosed for increasing circulating coronary blood flow. These treatments are useful for individuals who are expected to otherwise exhibit symptoms of reduced coronary circulation. Such individuals include those having coronary artery disease, angina, particularly unstable angina and Prinzmetal's angina, and coronary vasospasm. In accordance with the disclosed methods, coronary vasodilation is accomplished through the administration of effective amounts of buiprofen and/or flurbiprofen. At the indicated dosages, thromboxane synthesis is effectively inhibited without inhibiting prostacyclin synthesis. Flurbiprofen administration additionally results in thromboxane antagonism.
专利号:US-8540939-B2 优先权日:2008-04-28 标 题:Instrument and process for nanoparticles production in continuous flow mode 发明人:NIESZ KRISZTIAN; WOOTSCH ATILLA; GROUALLE MAXIME; OETVOES ZSOLT; DARVAS FERENC 权利人:NIESZ KRISZTIAN; WOOTSCH ATILLA; GROUALLE MAXIME; OETVOES ZSOLT; DARVAS FERENC; DARHOLDING VAGYONKEZELO KORLATOLT FELELOSSEGU TARSASAG 摘要:A continuous flow system for the synthesis of nanoparticles includes a feeding unit connected to the first reactor a flow path, at least one first reactor unit possessing a heatable reactor-zone, a second reactor unit which follows the first reactor in the same cascade; a mixing unit and a second feeding unit between the reactor units, and feeding pumps connected to a raw material source and/or a control unit which is capable of controlling at least one pressure controller and/or controlling the temperature of at least one heatable reactor-zone; each heatable reactor-zone is followed by a cooling unit in the cascade. In addition, a process for the synthesis of nanoparticles, preferably metal-containing nanoparticles, and nanoparticles of biologically active organic molecules wherein the process is accomplished using the system.
专利号:US-4337273-A 优先权日:1980-05-15 标 题:Methods of increasing coronary blood flow through vasodilation by flurbiprofen 发明人:LEFER ALLAN M 权利人:UNIV JEFFERSON 摘要:Novel treatments are disclosed for increasing circulating coronary blood flow. These treatments are useful for individuals who are expected to otherwise exhibit symptoms of reduced coronary circulation. Such individuals include those having coronary artery disease, angina, particularly unstable angina and Prinzmetal's angina, and coronary vasospasm. In accordance with the disclosed methods, coronary vasodilation is accomplished through the administration of effective amounts of ibuprofen and/or flurbiprofen. At the indicated dosages, thromboxane synthesis is effectively inhibited without inhibiting prostacyclin synthesis. Flurbiprofen administration additionally results in thromboxane antagonism.
专利号:US-2014026468-A1 优先权日:2012-07-24 标题:Control of Subterranean Termites 发明人:HENDERSON GREGG; WANG CAI; GAUTAM BAL K 权利人:HENDERSON GREGG; WANG CAI; GAUTAM BAL K; UNIV LOUISIANA STATE 摘要:A biological control is disclosed for termites, including subterranean termites such as C. formosanus , comprising a mixture of a chitin synthesis inhibitor such as lufenuron with a pathogen or opportunistic pathogen. The combination greatly enhances the effectiveness above that of the individual components. For example, P. aeruginosa is commonly found in association with termites, but it is not normally harmful to termites. However, in the presence of lufenuron, P. aeruginosa becomes an opportunistic pathogen that kills termites. As another example, B. thuringiensis , which otherwise has shown only limited effectiveness against termites, has greatly enhanced lethality in combination with lufenuron. In another aspect a termite toxicant is administered to termites in a clay-based bait. Clay acts as an attractant for subterranean termites such as C. formosanus , and a clay bait can increase a colony's consumption of a toxicant.
专利号:RU-2133733-C1 优先权日:1992-12-02 标题 :Method of synthesis of phenylpropionic acid
专利号:US-6171617-B1 优先权日:1996-02-20 标 题 :Effervescent ibuprofen preparation and process for the production thereof 发明人:GRUBER PETER 权利人:LOSAN PHARMA GMBH 摘要:In particular, the invention relates to a new, clearly dissolving ibuprofen effervescent formulation and a process for the preparation of this formulation. n Ibuprofen or (±)2-(4-isobutylphenyl)-propionic acid has the following structural formula n and has been for years a proven, non-steroidal antiphlogistic from the group of phenylpropionic acid derivatives, which shows effectiveness in veterinary experimental inflammation models by inhibiting prostaglandin synthesis.
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合成参考文献
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