CAS: 202865-66-5; (2-Bromo-5-Fluorophenyl)Methanol

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CAS号94569-84-3 2-溴-5-氟苯甲醛 | CAS号6942-39-8 2-溴-5-氟苯甲酸甲酯 | CAS号112399-50-5 2-溴-5-氟苄溴 | CAS号394-28-5 2-溴-5-氟苯甲酸 | CAS号452-63-1 2-溴-5-氟甲苯 | CAS号394-28-5 2-溴-5-氟苯甲酸 | CAS号94569-84-3 2-溴-5-氟苯甲醛 | CAS号857276-61-0 2-溴-5-氟苄氯 | CAS号112399-50-5 2-溴-5-氟苄溴 | CAS号174671-46-6 5-氟-1,3-二氢-1-羟基... | CAS号651326-68-0 1-bromo-2-(1-et... | CAS号842167-67-3 1-溴-4-氟-2-(甲氧基甲基)苯

2-溴-5-氟苯甲酸甲酯置于sodium Tetrahydroborate,Lithium Chloride,盐酸体系中,用 四氢呋喃,乙醇,水 用作溶剂,化学反应 0.17H,反应生成2-溴-5-氟苄醇
参考文献:基于4-苯基-6-(2,2,2-三氟-1-苯基乙氧基) 嘧啶的化合物及其应用方法
标题:基于4-苯基-6-(2,2,2-三氟-1-苯基乙氧基) 嘧啶的化合物及其应用方法
摘要:本发明涉及基于4‑苯基‑6‑(2,2,2‑三氟‑1‑苯基乙氧基)嘧啶的化合物及其应用方法.具体地,本发明公开了式i化合物,以及包含它们的组合物,以及它们用于治疗,预防和/或管理疾病或紊乱的方法:.

专利信息

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-6852711-B2
优先权日:1998-09-11
标题:HIV protease inhibitors
发明人：BOYER JR FREDERICK EARL; DOMAGALA JOHN MICHAEL; ELLSWORTH EDMUND LEE; GAJDA CHRISTOPHER ANDREW; HAGEN SUSAN ELIZABETH; LOVDAHL MICHAEL JAMES; LUNNEY ELIZABETH ANN; MARKOSKI LARRY JAMES; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:AGOURON PHARMA
摘要:The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.

专利号:CN-106431898-A
优先权日:2015-08-13
标 题:Synthesis and application of phenylpropionic acid derivatives