CAS: 1799328-86-1; 1-(6-(4-Fluorobenzyl)-5-(Hydroxymethyl)-3,3-Dimethyl-2,3-Dihydro-1H-Pyrrolo[3,2-B]Pyridin-1-yl)-2-((2R,5R)-5-Methyl-2-(((R)-3-Methylmorpholino)Methyl)Piperazin-1-yl)Ethanone

主要参考文献

1: Xiao R, An Y, Ye W, Derakhshan A, Cheng H, Yang X, Allen C, Chen Z, Schmitt NC, Van Waes C. Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy. Clin Cancer Res. 2019 Nov 1;25(21):6463-6474. doi: 10.1158/1078-0432.CCR-18-3802. Epub 2019 Jul 2.

合成参考文献

参考文献:10.1158/1078-0432.ccr-18-3802
摘要:Xiao R, An Y, Ye W, Derakhshan A, Cheng H, Yang X, Allen C, Chen Z, Schmitt NC, Van Waes C. Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy. Clin Cancer Res. 2019 Nov 01;25(21):6463–74.
参考文献:10.1016/j.bbrc.2022.02.053
摘要:Wang L, Hu C, Zhao Y, Hu X. Novel smac mimetic ASTX660 (Tolinapant) and TNF-α synergistically induce necroptosis in bladder cancer cells in vitro upon apoptosis inhibition. Biochemical and Biophysical Research Communications. 2022 Apr;602():8–14. doi: 10.1016/j.bbrc.2022.02.053.