CAS: 1643-26-1; 3-(2-Fluorophenyl)Propionic Acid

该化合物是一种含分子式C9H9FO2的氟芳芳烃碳酸衍生物,该化合物的特点是一个附于2-氟联苯环的丙诺酸链,使其成为有机合成和制药研究的宝贵中间体.氟代金增强了其活性和稳定性,有利于在生物活性分子(包括药物候选体和农用化学品)的开发过程中应用.其定义明确的结构和高纯度使其适合于精确的合成变异,例如混合反应和衍生.该化合物通常以白色到白白的晶状固体供应,具有统一的批到批量质量,确保研究和工业工艺的可靠性.

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143654-59-5 39856-89-8 134672-70-1

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报

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合成工艺路线路线简述

    📜2-Fluorobenzeneethanol Methanesulfonate (Ester)置于盐酸,氢氧化钾体系中,用 乙醇,水,N,N-二甲基甲酰胺 用作溶剂,化学反应 28.0H,反应生成3-(2-氟苯基)丙酸
    参考文献:Therapeutic Fluoroethylcyano Guanidines
    标题:Therapeutic Fluoroethylcyano Guanidines
    摘要:本文披露了具有如本文所述的化学式的化合物.还披露了与之相关的治疗方法,组成和药物.

    海关参考信息

    专利信息


    专利号:US-4033949-A
    优先权日:1976-04-14
    标 题:Analogs of thromboxane B2 and processes for their synthesis
    发明人：KELLY ROBERT C; NELSON NORMAN A
    权利人:UPJOHN CO
    摘要:The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B 2 (11β-homo-11a-oxa-PGF 2 .sub.α). These analogs are particularly and especially useful as reproductive cycle control agents.

    专利号:US-4070384-A
    优先权日:1976-04-14
    标 题 :Process for preparing thromboxane B compounds from prostaglandin fα co
    发明人：SCHNEIDER WILLIAM P
    权利人:UPJOHN CO
    摘要:The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B 2 (11β-homo-lla-oxa-PGF 2 α). These analogs are particularly and especially useful as reproductive cycle control agents.

    专利号:US-4052552-A
    优先权日:1976-08-20
    标 题:Thromboxane b analogs
    发明人：SCHNEIDER WILLIAM P
    权利人:UPJOHN CO
    摘要:The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B 2 (11β-homo-11a-oxa-PGF 2 α). These analogs are particularly and especially useful as reproductive cycle control agents.

    专利号:US-4054737-A
    优先权日:1976-08-20
    标 题 :Thromboxane B analogs
    发明人：KELLY ROBERT C; NELSON NORMAN A
    权利人:UPJOHN CO
    摘要:The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B 2 (11β-homo-11a-oxa-PGF 2 α). These analogs are particularly and especially useful as reproductive cycle control agents.

    专利号:US-4107427-A
    优先权日:1976-08-20
    标题 :Process and intermediates for preparing Thromboxane B1
    发明人：KELLY ROBERT C
    权利人:UPJOHN CO
    摘要:The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B2 (11 beta -homo-11a-oxa-PGF2 alpha ). These analogs are particularly and especially useful as reproductive cycle control agents.

    专利号:CN-112679336-A
    优先权日:2020-12-29
    标 题 :A kind of method of heterogeneous palladium metal catalyzed synthesis of phenylpropionic acid compounds

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    合成参考文献


    摘要:K. Bowden and D. C. Parkin, Can. J. Chem. 46, 3909 (1968).
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