CAS: 1603-40-3; 3-Methylpyridin-2-Amine

• 英文名称3-Methylpyridin-2-Amine
• 中文名称2-氨基-3-甲基吡啶
• IUPAC名称3-methylpyridin-2-amine
• 其它别名2-氨基-3-皮考林
• CAS编号1603-40-3
• MFCD编号:MFCD00006320
• EINECS号:216-501-4
• FDA UNII编号:Y2WWD85QY6
• 分子式:C6H8N2
• 分子量:108.14
• 产品CID: 806488
• 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: RGDQRXPEZUNWHX-UHFFFAOYSA-N
• InChI=1S/C6H8N2/c1-5-3-2-4-8-6(5)7/h2-4H,1H3,(H2,7,8)…
• 计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数0.0

相似化合物

物理性质

• 熔点29-31°C
• 沸点220.9°C at 760 mmHg
• 闪点118°C
• 密度1.1±0.1 g/cm3
• pKa:pK1: 7.24(+1) (25°C)
• PSA:38.91
• LogP:0.97222
• 折射率1.574
• 蒸汽压0.1±0.4 mmHg at 25°C
• 溶解性1000G/l
• 敏感性吸潮
• 外观形态透明黄色熔融后为液体
• 储存条件请置于阴暗处, 惰性气氛中,室温
• 产品应用用于有机合成.
• 性质描述黄色结晶.熔点32-34°C,沸点221-222°C,密度1.073g/mLat25°C,折光系数n20/D1.5823,闪点233°F

MSDS等安全信息

• GHS象形图
• GHS符号GHS06 & GHS08;
  注释: Skull and crossbones & Health hazard
• 危险类别急性毒性 类别3(吸入)
  急性毒性 类别3(经皮)
  急性毒性 类别3(经口)
  特定目标器官毒性-重复接触 类别2
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  急性毒性 类别2(经皮)
  皮肤腐蚀 类别1B
  严重眼损伤 类别1
  水生慢性毒性 类别3
• 警示词Danger(危险)
• 危险描述H331 |吸入会中毒.
  H311 |皮肤接触会中毒.
  H301 |吞咽会中毒.
  H373 |长期或反复接触可能损害器官.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H310 |皮肤接触致命.
  H314 |造成严重皮肤灼伤和眼损伤.
  H318 |造成严重眼损伤.
  H412 |对水生生物有害并具有长期持续影响.
• 防范说明P260-P262-P264-P270-P271-P273-P280-P301+P330+P331-P303+P361+P353-P362-P403+P233-P405-P501
• 危险等级8
• UN编号1760.0
• 危险品标志T
• 包装等级Ⅱ
• 安全声明36/37/39-45-37/39-28A-26
• 危险类别码23/24/25-33-36/37/38-25
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 1603-40-3 + 1878-67-7 = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C2.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  2761761-94-6 = 1603-40-3 + 84194-36-5
  反应条件:1.1 Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,Rt
  标题:From Amides To Urea Derivatives Or Carbamates With Chemospecific C-C Bond Cleavage At Room Temperature
  作者:Lv,Cong; Liu,Dan; Muschin,Tegshi; Bai,Chaolumen; Bao,Agula; Et Al
  参考文献:Organic Chemistry Frontiers 日期:2022 卷标:9(5) 页码:1354-1363]
  
  = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  1003-03-8 = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen,Tetrabutylammonium Hydrogen Sulfate Catalysts: Cupric Acetate Solvents: Acetonitrile; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen,Tetrabutylammonium Hydrogen Sulfate Catalysts: Cupric Acetate Solvents: Acetonitrile; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  100-51-6 = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen,Tetrabutylammonium Hydrogen Sulfate Catalysts: Cupric Acetate Solvents: Acetonitrile; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157]
  
  1017324-23-0 = 1603-40-3 + 81316-36-1
  反应条件:1.1 Reagents: Oxygen,Tetrabutylammonium Hydrogen Sulfate Catalysts: Cupric Acetate Solvents: Acetonitrile; 6 H,80 °C2.1 Reagents: 1-Hydroxybenzotriazole,1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Solvents: Tetrahydrofuran; Overnight,25 °C3.1 Reagents: Oxygen Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,80 °C
  标题:Copper-Catalyzed Transamidation Of Unactivated Secondary Amides Via C-H And C-N Bond Simultaneous Activations
  作者:Lv,Cong; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(4) 页码:2140-2157

海关参考信息

• 2933310010-吡啶
  2939800000-其他生物碱
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管