专利号:US-10954178-B1 优先权日:2020-08-28 标题 :Synthesis of haloindenes 发明人:WNUK STANISLAW F; HOWLADER MD ABU HASAN 权利人:WNUK STANISLAW F; HOWLADER MD ABU HASAN; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES 摘要:The subject invention provides an expedited synthesis of 5, 6, and 7-iodoindenes from the corresponding aminoindan-1-ones in more than 70% yield, employing readily available precursors and reagents. A three-step sequence involves diazotization-iodination of aminoindan-1-one followed by reduction and dehydration. The method has a general character and can be extended for the preparation of various 4-, 5-, 6- or 7-haloindenes using different halogen sources for diazotization-halogenation reaction.
专利号:WO-9741109-A1 优先权日:1996-04-26 标 题 :Synthesis of (±) - calicheamicinone, precursors, intermediates and derivatives 发明人:CLIVE DERRICK L J; DAIGNEAULT SYLVAIN; BO YUNXIN; TAO YONG 权利人:UNIV ALBERTA; CLIVE DERRICK L J; DAIGNEAULT SYLVAIN; BO YUNXIN; TAO YONG 摘要:This invention relates to calicheamicinone and related compounds, and processes for the preparation of these compounds and derivatives or analogs thereof. Many of the products that can be synthesized using these compounds have antibiotic activity including, but not limited to, anticancer, antifungal or antimicrobial activity.
专利号:US-5693792-A 优先权日:1992-02-18 标 题 :β-lactam and cephem compounds and processes for their production 发明人:TORII SHIGERU; TANAKA HIDEO; SASAOKA MITIO; SHIROI TAKASHI; KAMEYAMA YUTAKA 权利人:OTSUKA KAGAKU KK 摘要:The object of the invention is to provide a β-lactam compound and a 2-substituted methyl-3-cephem compound, both of which are of value as intermediates for the synthesis of cephem antibiotics. n The β-lactam compound of the invention may be represented by the general formula ##STR1## wherein R 1 represents a protected amino group, for instance; R 2 represents hydrogen, for instance; R 3 represents hydrogen or a carboxy-protecting group; R 4 represents an aryl group which may be substituted; R 5 represents an alkenyl group which may be substituted, for instance. The 2-substituted methyl-3-cephem compound of the invention may be represented by the general formula ##STR2## wherein R 1 , R 2 and R 3 are as defined above; R 6 represents an aryl group which may be substituted.
专利号:TW-I458750-B 优先权日:2011-05-05 标题 :Synthesis of low energy gap carbazole copolymerized polymer with electron donor-electron acceptor-electron donor monomer structure and its application in organic polymer solar cell
专利号:EP-1935869-A1 优先权日:2000-10-02 标题:Retinoids for the treatment of emphysema 发明人:LAPIERRE JEAN MARC; ROTSTEIN MARC; SJOGREN ERIC BRIAN 权利人:HOFFMANN LA ROCHE 摘要:The current invention provides novel retinoid compounds and methods for their synthesis, the use of such compounds for the preparation of medicaments for treating or preventing emphysema, cancer and dermatological disorders, methods for such deseases and pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and dermatological disorders.
专利号:AT-521203-A1 优先权日:2018-05-14 标题:Synthesis of alkylthio-substituted poly (p-phenylene-vinylene) polymers