CAS: 102-14-7; 4-Oxo-4-(Phenylamino)Butanoic Acid

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17722-52-0 5415-22-5 188011-68-9

上下游产品

CAS号108-30-5 丁二酸酐 | CAS号5430-83-1 methyl 3-(pheny... | CAS号4837-33-6 2-nitro-N-pheny... | CAS号83-25-0 N-苯基琥珀酰亚胺 | CAS号538-51-2 N-苄叉苯胺 | CAS号110-15-6 琥珀酸； 丁二酸 | CAS号15510-09-5 Butanediamide,N... | CAS号102-08-9 二苯基硫脲 | CAS号3563-14-2 磺胺琥珀酸 | CAS号1797-93-9 AKOS BBS-00001823 | CAS号83-25-0 N-苯基琥珀酰亚胺 | CAS号7732-18-5 水 | CAS号25589-41-7 4-[(4-溴苯基)氨基]-4-氧代丁酸 | CAS号15510-09-5 Butanediamide,N... | CAS号5470-06-4 4-(2,5-二氧代吡咯烷-1... | CAS号5502-63-6 4'-硝基硫辛酸 | CAS号5430-83-1 methyl 3-(pheny... | CAS号40265-98-3 4-oxo-4-[[4-[(2...

📜N-苯丁二醯亞胺置于ammonium Hydroxide,甲基锂,Calcium Carbonate体系中,化学反应生成琥珀酸一酰苯胺
参考文献:Menschutkin,Justus Liebigs Annalen Der Chemie,1872,Vol. 162,P. 166
标题:Menschutkin,Justus Liebigs Annalen Der Chemie,1872,Vol. 162,P. 166

专利信息

专利号:US-7390801-B2
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PLEISS MICHAEL A; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES A; REEL JON K; DRESSMAN BRUCE A; DROSTE JAMES J; HENRY STEVEN S; STUCKY RUSSELL D; PORTER WARREN J
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-5077397-A
优先权日:1988-11-29
标题:Sialic acid derivative with active ester groups
发明人：YOSHIMURA SHOJI; TANAKA MAKOTO
权利人:KANTO ISHI PHARMA CO LTD
摘要:Sialic acid derivative with active ester groups expressed with the formula [I] ##STR1## Where R 1 denotes hydrogen or an acetyl group, R 2 denotes hydrogen or a lower alkyl group, R 3 denotes C 2 H 4 , C 3 H 6 or C 2 H 2 , R 4 denotes an hydroxyl group, the residue left after removing hydrogen from the alcohol portion of the active ester or alkyloxycarbonyloxy group, AC denotes an acetyl group, Ph denotes an phenyl group, and X denotes oxygen or sulfur. This sialic acid derivative has high reactivity because it has active ester groups in the molecules and can be used as a raw material or intermediate for synthesis of various sialic acid derivatives.

专利号:US-2002045747-A1
优先权日:1996-12-23
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2002052359-A1
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting B-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2002173504-A1
优先权日:1996-12-23
标题 :Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting B-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2004043977-A1
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds