1-(2,4-二甲基苯基)-2-甲基丙烷置于三氯化铁体系中,化学反应生成 1-叔丁基-3,5-二甲苯 参考文献:The Action Of Anhydrous Ferric Chloride On Alkylbenzenes1 标题:The Action Of Anhydrous Ferric Chloride On Alkylbenzenes1 摘要: DOI:10.1021/ja01846A061
专利号:US-2003162992-A1 优先权日:2001-12-14 标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides 发明人:WATANABE KYOICHI A; DU JINFA 摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-6355826-B1 优先权日:1997-09-17 标题:Synthesis of stable nitrile oxide compounds 发明人:PARKER DANE KENTON 权利人:GOODYEAR TIRE & RUBBER 摘要:This invention discloses a process for the synthesis of stable aryl nitrile oxides which comprises the sequential steps of (1) halomethylating a halomethyl group onto a substituted aromatic compounds wherein said halomethyl group is halomethylated onto a position that is ortho to at least one of the substituent groups on the substituted aromatic compound; (2) converting the ortho halomethylated-substituted aromatic compound into an ortho-substituted aromatic aldehyde by reacting the ortho halomethylated-substituted aromatic compound with a salt selected from the group consisting of sodium 2-nitropropane and potassium 2-nitropropane in a lower alcohol solvent; (3) converting the ortho-substituted aromatic aldehyde into an ortho-substituted aromatic; and (4) converting the ortho-substituted aromatic oxime into the ortho-substituted aryl nitrile oxide by reacting the ortho-substituted aromatic oxime with an aqueous sodium hypochlorite solution.
专利号:US-6197920-B1 优先权日:1999-07-21 标 题:Formulation for the production of 1, 3-bis (4-aminophenoxy) naphthalene and its polymer 发明人:CHENG KUN LIN; CHEN WEN-TUNG 权利人:CHINA TEXTILE INST 摘要:The present invention relates to the synthesis of new type of diamine monomer, 1,3-bis(4-amonophenoxy)naphthalene, and with such a compound to produce a series of aromatic polymers, including polyamide, polyimide, copoly(amide-imide)s, etc., such polymers having excellent resistance to heat and mechanical properties.
专利号:US-3992435-A 优先权日:1975-04-07 标 题:Process for electrolytic synthesis of polyalkylbiphenylpolycarboxylic acid compounds 发明人:DONOHUE JOHN A; FIELDS ELLIS K; HART HAROLD 权利人:STANDARD OIL CO INDIANA 摘要:Process for coupling alkyl esters of polyalkylbenzoic acid to prepare polyalkylbiphenylpolycarboxylic acid compounds which comprises anodically oxidizing said alkyl esters in a non-nucleophilic media by applying a source of direct current in liquid phase at atmospheric pressure and temperatures from -30 DEG to 80 DEG C. The biphenyl acid compounds are useful in the formation of polyester resins, including alkyds, and fiber-forming polymers.
专利号:US-8853228-B2 优先权日:2007-06-04 标 题:Heterocyclic analogs of propargyl-linked inhibitors of dihydrofolate reductase 发明人:ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE 权利人:ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE; UNIV CONNECTICUT 摘要:The compositions and methods described herein disclose the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as Bacillus anthracis and methicillin-resistant Staphylococcus aureus , fungi such as Candida glabrata, Candida albicans and Cryptococcus neoformans and protozoa such as Cryptosporidium hominis and Toxoplasma gondii . These compounds and other similar compounds are also potent against the mammalian enzyme and may be useful as anti-cancer therapeutics.
专利号:US-7977269-B2 优先权日:2005-07-21 标 题:Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization 发明人:SMALL BROOKE L; CARNEY MICHAEL 权利人:CHEVRON PHILLIPS CHEMICAL CO 摘要:Novel α-diimine metal complexes, particularly iron complexes, having a phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are disclosed. The α-diimine metal complexes having a phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are produced by forming one of the α-diimine metal complex imine bonds in the presence of a metal salt or an α-acylimine metal complex. The α-diimine metal complexes having phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are useful for polymerizing or oligomerizing olefins.