CAS: 6320-96-3; 3-Bromopropionamide

该化合物是一种有机化合物,其特征是含有一种附于丙酰胺结构的溴原子,其特性是:它一般是白色的对白的固体,在水和酒精等极地溶剂中可溶解;该化合物由于具有可参与核生殖替代反应的溴原子的存在而具有反应性而闻名于此;Bromopropoimide,经常用于有机合成,特别是用于制作各种药品和农用化学品;其分子结构包括一种丙酰胺功能组,该组有助于其作为化学反应中的潜在构件的特性;在处理该化合物时,需要安全防范,因为如果吸入,摄取或接触皮肤,可能会对健康造成危害;建议在一个冷却,干燥的地方储存不相容的物质,以保持其稳定性和功效.

结构式图片

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5003-71-4 15102-42-8 541-35-5

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上下游产品

3-bromopropanoyl is°Cyanate 3-Bromopropionyl chloride 3-Bromo-propionimidic acid ethyl ester 3-chloropropionamide [4-(2-carbamoyl-ethylamino)-phenyl]-arsonic acid pyrimidin-4-ylthio)propionamideα-(1-phenylpyrazolo3,4-dpyrimidin-4-ylthio)propionamide pyrimidin-6-ylthio)propionamideα-(4-mercapto-1-phenylpyrazolo3,4-dpyrimidin-6-ylthio)propionamide 3-[7-(4-Methoxy-benzyl)-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-yl]-propionamide

合成工艺路线路线简述

  • 合成目标产物 3-Bromopropionamide 主要起始原料 N-Bromosuccinimide And Benzene
  • (文献来源)合成步骤主要原料 N-Bromosuccinimide 和 Benzene
📜3-溴丙酰异氰酸酯置于四氢呋喃,水体系中,化学反应生成 3-溴丙胺
参考文献:The Synthesis And Solvolysis Of The 2-Halo-1,4-Endoxocyclohexanes1
标题:The Synthesis And Solvolysis Of The 2-Halo-1,4-Endoxocyclohexanes1
摘要:
DOI:10.1021/ja01567A047

海关参考信息

专利信息


专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人:MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:US-8912150-B2
优先权日:2001-08-03
标题:Ribosome structure and protein synthesis inhibitors
发明人:STEITZ THOMAS A; MOORE PETER B; SUTCLIFFE JOYCE A; OYELERE ADEGBOYEGA K; IPPOLITO JOSEPH A
权利人:RIB X PHARMACEUTICALS INC; UNIV YALE; MELINTA THERAPEUTICS INC
摘要:The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.

专利号:US-5508389-A
优先权日:1990-09-27
标题 :Process for producing concentrated aqueous solutions of anionic azo dyes
发明人:MISCHKE PETER; HOHMANN KURT; SCHWAB ECKHARD; SITTIG MANFRED
权利人:HOECHST AG
摘要:PCT No. PCT/EP91/01830 Sec. 371 Date Mar. 26, 1993 Sec. 102(e) Date Mar. 26, 1993 PCT Filed Sep. 25, 1991 PCT Pub. No. WO92/06140 PCT Pub. Date Apr. 16, 1992.If highly concentrated aqueous solutions of azo dyes are prepared directly by diazotization and coupling reactions, appreciable difficulties generally result as a consequence of the fact that the diazotization and coupling reactions give rise to viscous phases which lead to stirring problems in the reaction apparatus used, which in turn results in an incomplete synthesis. The novel process for preparing concentrated aqueous dye solutions of an anionic dye in an aqueous medium overcomes this disadvantage by carrying out the diazotization of the aromatic amine diazo component and/or the coupling reaction between the diazonium salt and the coupling component in the presence of an auxiliary which exerts a viscosity-reducing effect on pasty phases. Examples of such auxiliaries are optionally alkyl-substituted naphthalenesulfonic acid-formaldehyde condensation products, ligninsulfonates, polyacrylates and copolymers of maleic anhydride and methacrylic acid or acrylic acid.

专利号:EP-0040896-B1
优先权日:1978-08-22
标题:Synthesis of amides

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides

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