CAS: 23451-96-9; 2-Amino-5-Methylbenzenethiol

该化合物是一种有机化合物,其特点是存在一个氨基氨基氨基-甲基-2-氨基硫酚(-NH2)和一个含有一个甲基组(-CH3)的苯环附属硫醇(-SH),该化合物具有一个分子结构,其中包括一个由六人组成的芳香环,在2和5个位置上具有分体.该化合物一般在室内温度下是固体,可能因硫醇组而表现出一种特质.氨基和硫醇的功能都允许多种再活动,使该化合物在各种化学合成和应用中有用,包括作为染料,制药和农用化学生产中的一种潜在中间体.此外,该化合物可能具有诸如极溶剂中的溶性以及受现有功能组影响的不同程度的酸性和基本性等特性.在处理该化合物时,应当采取安全防范措施,因为硫柳子具有毒性并具有强的成分.

结构式图片

相似化合物

39484-01-0 76462-17-4 100601-29-4

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合成工艺路线路线简述

    📜4-甲基苯胺盐酸盐置于二氯化二硫,溶剂黄146体系中,化学反应生成2-氨基-5-甲基苯硫酚
    参考文献:De370854
    标题:De370854

    海关参考信息

    专利信息


    专利号:WO-2011106929-A1
    优先权日:2010-03-02
    标题:Inhibitors of hepatitis c virus ns5b polymerase
    发明人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO
    权利人:MERCK SHARP & DOHME; ANGELETTI P IST RICHERCHE BIO; MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO
    摘要:Compounds of formula I that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infection and for inhibiting HCV viral replication and /or viral production in a cell-based system.

    专利号:US-2012328569-A1
    优先权日:2010-03-02
    标题:Inhibitors of hepatitis c virus ns5b polymerase
    发明人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
    权利人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
    摘要:Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:BR-PI0113470-B1
    优先权日:2000-08-24
    标 题 :COMPOSITION OF AMYLOID CONNECTION, PHARMACEUTICAL COMPOSITION AND COMPOSITION SYNTHESIS METHODS, IN VIVO DETECTION OF AMILOID DEPOSITS IN AN INDIVIDUAL AND IN HUMAN OR ANIMAL TISSUE, QUANTIFICATION OF AMILOID DEPOSIT AND DIAGNOSIS OF DENOUS TISSUE ALZHEIMER OF A NORMAL BRAIN

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Wilkins, D. J.; Bradley, P. A., Science of Synthesis, (2004) 13, 268.
    摘要:Ulrich, H., Science of Synthesis, (2004) 17, 130.
    摘要:Rakitin, O. A., Science of Synthesis, (2007) 31, 966.
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