CAS: 2279-16-5; (S)-2-(2-Chloroacetamido)-3-Methylbutanoic Acid

该化合物是一种氨酸衍生物,其特点是存在附属于L-valine结构氮的氯乙酰基体,该化合物一般是白色的脱白晶体固体,由于水和甲醇等极地溶剂的氨基和碳酸功能组,可溶于水和甲酸等极地溶剂;氯乙酰胺酮引入了再活性,使其在各种化学合成应用中有用,特别是在制药和农用化学品开发中.

结构式图片

相似化合物

20051-64-3 4090-17-9 101072-54-2

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号1963-21-9 甘氨酰-L-缬氨酸 | CAS号72-18-4 l-缬氨酸 | CAS号79-11-8 氯乙酸 | CAS号516-06-3 DL-缬氨酸

合成工艺路线路线简述

    📜甘氨酰-L-缬氨酸置于亚硝酰氯体系中,用 甲酸 用作溶剂,化学反应生成氯乙酰-L-缬氨酸
    参考文献:Patton,W. Et Al.,Australian Journal Of Chemistry,1969,Vol. 22,P. 2709-2712
    标题:Patton,W. Et Al.,Australian Journal Of Chemistry,1969,Vol. 22,P. 2709-2712

    海关参考信息

    专利信息


    专利号:US-5219741-A
    优先权日:1989-09-06
    标题:Method of making L-proline using an N-acyl-L-protine acylase
    发明人:GROEGER ULRICH; LEUCHTENBERGER WOLFGANG; DRAUZ KARLHEINZ
    权利人:DEGUSSA
    摘要:A microbiologically produced, thermostable N-acylproline-acylase and a process for obtaining it from Comamonas testosteroni DSM 5416 and Alcaligenes denitrificans DSM 5417. The enzyme is useful for the synthesis of L-proline from various N-acyl-L-proline derivatives.

    专利号:US-5120652-A
    优先权日:1989-09-06
    标 题 :Substantially purified n-acyl-l-proline acylase from comamonas testosteroni dsm 5416 and alcaligenes denitrificans dsm 5417
    发明人:GROEGER ULRICH; LEUCHTENBERGER WOLFGANG; DRAUZ KARLHEINZ
    权利人:DEGUSSA
    摘要:A substantially purified N-acyl-L-proline-acylase from Comamonas testosteroni DSM 5416 and Alcaligenes denitrificans DSM 5417. The enzyme is useful for the synthesis of L-proline from various N-acyl-L-proline derivatives.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: S Tokuyama, Et Al. Purification And Properties Of Thermostable N-Acylamino Acid Racemase From Amycolatopsis Sp. Ts-1-60. Appl Microbiol Biotechnol. 1995 Mar;42(6):853-9.

    合成参考文献


    摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 441.
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