CAS: 20588-68-5; N,N-Diethylsulfamoyl Chloride

该化合物是一种有机化合物,其特点是存在一种磺酰胺功能组,它一般是无色的,青黄液体,由于氯化物存在而闻名其反应性,使它在有机合成中成为有用的中间体.该化合物在有机溶剂中溶解,但在水中溶解性有限.主要用于合成各种药品和农用化学物,它作为较复杂的分子的建筑块.二乙基磺酰氯在分解时释放有毒气体,特别是在接触水分或高温时,需要小心处理和储存.此外,如果通过皮肤吸入或吸收,它可能会对健康造成危害,强调在实验室或工业环境中使用适当安全措施的重要性.

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合成工艺路线路线简述

    📜N-Chlorodiethylamine置于二氧化硫体系中,用 四氯化碳 用作溶剂,化学反应生成二乙基磺酰氯
    参考文献:Petrov,K.A. Et Al.,Journal Of General Chemistry Of The Ussr,1961,Vol. 31,P. 1265-1269
    标题:Petrov,K.A. Et Al.,Journal Of General Chemistry Of The Ussr,1961,Vol. 31,P. 1265-1269

    海关参考信息

    专利信息


    专利号:US-2024368075-A1
    优先权日:2021-07-02
    标题 :Synthesis of N,N-Dialkyl, -Dialkenyl, -Dialkynyl, and Related Cyclics, Sulfamoyl Fluoride Compounds Using Hydrogen Fluoride
    发明人:SINGH RAJENDRA P; HU QICHAO
    权利人:SES HOLDINGS PTE LTD
    摘要:Methods of producing N,N-dimethyl sulfamoyl fluoride and related derivatives of the formula F—S(O)2—NR2 (I) by contacting a sulfamoyl nonfluorohalide compound of the formula X—S(O)2—NR2 (II) with anhydrous hydrogen fluoride under conditions sufficient to produce the N,N-dimethyl sulfamoyl fluoride or derivative thereof of Formula I, wherein R in each of Formulas I and II is, independently, a linear or branched alkyl, alkenyl, or alkynyl group containing 1 to 12 carbon atoms, the Rs can be joined to form a cyclic amine with the N, and X is any one of chlorine, bromine, and iodine.

    专利号:US-2023322661-A1
    优先权日:2020-08-21
    标题 :Synthesis of N,N-Branched Sulfamoyl Fluoride Compounds Using Bismuth Trifluoride
    发明人:SINGH RAJENDRA P; HU QICHAO; SHEIMAN JOHNATHAN
    权利人:SES HOLDINGS PTE LTD
    摘要:Methods of producing N,N-branched sulfamoyl fluoride compounds of the formula F-S(O) 2 -NR 2 by contacting bismuth trifluoride with an N,N-branched sulfamoyl nonfluorohalide compound of the formula X-SO 2 NR 2 , wherein X=chlorine (Cl), bromine (Br), or iodine (I), and each R is, independently, a linear or branched alkyl, fluoroalkyl, alkenyl, fluoroalkenyl, alkynyl, or fluoroalkynyl with 1 to 12 carbon atoms, to fluorinate the N,N-branched sulfamoyl nonfluorohalide compound. This is a non-aqueous method, the purity of product is very high, and the desired product can be isolated in quantitative yield. The N,N-branched sulfamoyl fluoride compounds so produced are useful in various applications including as electrolyte solvents and additives in electrochemical devices, such as lithium batteries and capacitors, and in biological fields, among others.

    专利号:US-7429680-B2
    优先权日:2004-02-17
    标 题:Synthesis of sterically hindered secondary aminoether alcohols
    发明人:SISKIN MICHAEL; KATRITZKY ALAN ROY; KIRICHENKO KOSTYANTYN MYKOLAYE
    权利人:EXXONMOBIL RES & ENG CO
    摘要:Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or a mixed sulfuryl amide halide to yield a sulfonic-carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then aminated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

    专利号:EP-4200277-A1
    优先权日:2020-08-21
    标题 :Synthesis of n,n-branched sulfamoyl fluoride compounds using bismuth trifluoride

    专利号:US-2007219400-A1
    优先权日:2004-02-17
    标 题 :Synthesis of Sterically Hindered Secondary Aminoether Alcohols

    专利号:WO-2023275607-A1
    优先权日:2021-07-02
    标 题 :Synthesis of n,n-dialkyl, -dialkenyl, -dialkynl, and related cyclics, sulfamoyl fluoride compounds using hydrogen fluoride

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 808.
    摘要:Sherman, E. S.; Chemler, S. R., Science of Synthesis, (2009) 40, 1293.
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