CAS: 18037-10-0; N-(Trimethylsilyl)-2-((Trimethylsilyl)Oxy)Pyrimidin-4-Amine

相似化合物

3289-47-2 5621-01-2 41381-21-9

上下游产品

CAS号71-30-7 胞嘧啶 | CAS号999-97-3 六甲基二硅氮烷 | CAS号75-77-4 三甲基氯硅烷 | CAS号72525-60-1 hexa-methyldisi... | CAS号25561-30-2 N,O-双(三甲基硅烷基)三氟乙酰胺 | CAS号17857-70-4 三丁基(环丙基)锡 | CAS号50271-92-6 5-bromo-N-trime... | CAS号10416-59-8 N,O-双(三甲基硅基)乙酰胺 | CAS号7481-89-2 2',3'-二脱氧胞苷 | CAS号134790-40-2 1'-表吉西他滨3',5'-二苯甲酸酯 | CAS号134790-39-9 2'-脱氧-3',5'-二-O... | CAS号78137-49-2 2-[(4-amino-2-o... | CAS号68724-12-9 4-amino-1-(2-hy...

📜胞嘧啶 反应生成N-(三甲基硅基)-2-(三甲基硅氧基)-4-嘧啶胺
参考文献:J. Org. Chem. 1988,53,4786-4789
标题:J. Org. Chem. 1988,53,4786-4789

专利信息

专利号:US-2007042987-A1
优先权日:2004-07-30
标题:Stereoselective synthesis of beta-nucleosides
发明人：LIN KO-CHUNG; LI WENSEN; LIN CHUNHUI; YUNGSHUN WEIN; KUO-HIS KAO
权利人:LIN KO-CHUNG; LI WENSEN; LIN CHUNHUI; YUNGSHUN WEIN; KUO-HIS KAO
摘要:This invention relates to a process of stereoselectively synthesizing an alcohol of the following formula: n n nwherein R 1 , R 2 , R 3 , R 4 , and R 5 are defined in the specification. The process includes reacting (R) 4-formyl-2,2-dimethyldioxolane with α-bromoacetate in the presence of Zn and a Zn activating agent.

专利号:US-7485716-B2
优先权日:2005-05-02
标题:Stereoselective synthesis of β-nucleosides
发明人：LIN KO-CHUNG; LI WENSEN
权利人:PHARMAESSENTIA CORP
摘要:This invention relates to a process for stereoselectively preparing a nucleoside of the following formula: n nwherein R 3 , R 4 , and B are defined herein. The process includes reacting a furanose compound with a nucleobase in the presence of a halide salt. Also disclosed is another process for stereoselectively synthesizing an intermediate that can be used to make the starting compound in the first-mentioned process.

专利号:US-8193339-B2
优先权日:2007-11-06
标 题 :Synthesis of β-nucleosides
发明人：CHU CHI-YUAN; LEE WEI-DER; LI WENSEN; HWANG CHAN KOU
权利人:CHU CHI-YUAN; LEE WEI-DER; LI WENSEN; HWANG CHAN KOU; PHARMAESSENTIA CORP
摘要:This invention relates to a process of stereoselectively synthesizing a β-nucleoside compound of formula (I): n nwherein R 1 , R 2 , and B are as defined in the specification; each of R 3 and R 4 , independently, is H or fluoro. The process includes reacting, in the presence of a transition metal salt, a tetrahydrofuran compound of formula (II):n n nwherein R 1 , R 2 , and L are as defined in the specification, with a nucleobase derivative; and each of R 3 and R 4 , independently, is H or fluoro.

专利号:US-9790252-B2
优先权日:2009-07-01
标 题 :2-fluorinated riboses and arabinoses and methods of use and synthesis
发明人：SAUVE ANTHONY A; CEN YANA
权利人:SAUVE ANTHONY A; CEN YANA; UNIV CORNELL
摘要:Disclosed are halogenated 2-deoxy-lactone, 2′-deoxy-nucleosides, and derivatives thereof, for example, a compound of formula (I). Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one compound or salt of the invention, and a method of treating a disorder is selected from the group consisting of an abnormal cellular proliferation, a viral infection, and an autoimmune disorder.

专利号:US-2007015914-A1
优先权日:2005-05-02
标 题:Stereoselective synthesis of beta-nucleosides

专利号:WO-2009061894-A1
优先权日:2007-11-06
标 题 :Novel synthesis of beta-nucleosides