CAS: 148355-75-3; 3-(Methylsulfonylamino)Phenylboronic Acid
该化合物是一种有机化合物,其特点是存在一种碱酸功能组,众所周知,该组具有与二醇形成可逆共价结合的能力.该化合物具有一种代之以甲烷硫磺基氨基组的苯基环,增强了其溶性与再活性.甲烷硫基氨基酸有助于其作为有机合成的多功能构件的潜力,特别是在制药和农用化学的开发方面.该二酸功能允许参与铃木-米亚乌拉的交叉反应,使其在形成碳结层时具有价值.此外,该化合物可能具有中度稳定性,例如在标准条件下对湿度和空气具有敏感性,需要小心处理和储存.其应用范围扩大到医药化学,在生物活性分子合成中可以作为铅化合物或中间体.
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305448-92-4 380430-57-9 850623-67-5物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
专利信息
专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.
