CAS: 133-65-3; Sodium 3,3'-((Sulfonylbis(4,1-Phenylene))Bis(Azanediyl))Bis(1-Phenylpropane-1,3-Disulfonate)
- 英文名称Sodium 3,3'-((Sulfonylbis(4,1-Phenylene))Bis(Azanediyl))Bis(1-Phenylpropane-1,3-Disulfonate)
- 中文名称苯丙砜
- IUPAC名称sodium 3,3'-((sulfonylbis(4,1-phenylene))bis(azanediyl))bis(1-phenylpropane-1,3-disulfonate)
- 其它别名Solasulfone; Sulfetrone; Sulphetrone; Solapsone; 1,1'-[sulfonylbis(4,1-Phenyleneimino)]Bis[3-Phenyl-1,3-Propanedisulfonic Acid] Tetrasodium; Cimedone; Solasulfone Usp/ep/bp
- CAS编号133-65-3
- MFCD编号:MFCD00301905
- EINECS号:205-116-7
- FDA UNII编号:H12JE4313S
- 分子式:C30H28N2Na4O14S5分子量:892.85
- 产品CID: 506826
- 同类组份化合物CAS133-65-3 (free base); 144-75-2 (sodium)
- 产品分类原料药 → 人工合成抗感染类药 → 抗结核麻风分支杆菌类药
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海关参考信息
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专利信息
专利号:US-9149445-B2
优先权日:2009-07-27
标 题:Inhibition of glycerol-3-phosphate acyltransferase (GPAT) and associated enzymes for treatment of viral infections
发明人：LIU SEAN; RABINOWITZ JOSHUA D; SHENK THOMAS
权利人:LIU SEAN; RABINOWITZ JOSHUA D; SHENK THOMAS; UNIV PRINCETON
摘要:A method of treating or preventing a viral infection in a mammal by administering a compound or pharmaceutically acceptable derivative thereof that inhibits a phosphatidic acid synthesis enzyme.
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主要参考文献
1: Peters JH, Murray JF Jr, Gordon GR. The disposition of sulfoxone and solasulfone in leprosy patients. Lepr Rev. 1975 Sep;46(3):171-80. doi: 10.5935/0305-7518.19750018. 129(1):48-9. Russian. therapeutics and toxicology. Lancet. 1948 Jul 24;2(6517):131-4. doi: 10.1016/s0140-6736(48)90494-2. 3(4):455. Italian. pharmacology and chemotherapy. Br J Pharmacol Chemother. 1948 Mar;3(1):15-28. doi: 10.1111/j.1476-5381.1948.tb00348.x.
6: MORLOCK HV, LIVINGSTONE R. Sulphetrone in pulmonary tuberculosis. Lancet. 1949 Dec 24;2(6591):1170. doi: 10.1016/s0140-6736(49)91827-9. 2(6518):174-9. doi: 10.1016/s0140-6736(48)90536-4. 21(1):30-4. doi: 10.5935/0305-7518.19500004. 62(2):160-9. doi: 10.1164/art.1950.62.2.160. 2(6518):180-2. doi: 10.1016/s0140-6736(48)90537-6.
合成参考文献
摘要:British Journal of Pharmacology and Chemotherapy., 3(15), 1948
摘要:American Review of Tuberculosis., 60(62), 1949
摘要:Arzneimittel-Forschung. Drug Research., 5(213), 1955 []
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