CAS: 481-53-8; 5,6,7,8-Tetramethoxy-2-(4-Methoxyphenyl)-4H-Chromen-4-One

上下游产品

5,8-dihydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4-benzopyrone dimethyl sulfate 5,6,7,8,4'-penta methoxyl-flavanone 6-hydroxy-4',5,7,8-tetramethoxyflavone2-hydroxy-3,4,5,6-tetramethoxyacetophenone 76988NSC76988 4'-benzyloxy-5,6,7,8-tetramethoxyflavone 4'-hydroxy-5,6,7,8-tetramethoxy flavone

(E)-1-(2-羟基-4,6-二甲氧基苯基)-3-(4-甲氧基苯基)-2-丙烯-1-酮置于吡啶,碘,二甲基二环氧乙烷,三溴化硼,Potassium Carbonate体系中,用 二氯甲烷,丙酮 作为反应溶剂,化学反应 13.83H,反应生成 桔皮素
参考文献:Regioselective Hydroxylation Of 2-Hydroxychalcones By Dimethyldioxirane Towards Polymethoxylated Flavonoids
标题:Regioselective Hydroxylation Of 2-Hydroxychalcones By Dimethyldioxirane Towards Polymethoxylated Flavonoids
摘要:The Flavone Nucleus Is Part Of A Large Number Of Natural Products And Medicinal Compounds. In This Presentation The Novel Regioselective Hydroxylation Of Hydroxyarenes With Dmd Is Described. The Results Showed Further That Flavonoids With 5-Hydroxy Group Were Selectively Oxyfunctionalized At The Para-Position C8 Carbon Atom By Dmd. Finally,According To This Methodology,The Naturally occurring Isosinensetin,Tangeretin,Sinensetin,Nobiletin,Natsudaidain,Gardenin B,3,3',4',5,6,7,8-Heptamethoxyflavone,Quercetin And Its Derivatives Were Synthesized. (C) 2004 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2004.01.023

专利信息

专利号:WO-2025081225-A1
优先权日:2023-10-17
标 题 :Synthesis of polyphenols
发明人：TURLAND CADE LACHLAN; GROLMAN DAVID; BEHRENDORFF JAMES BRUCE YARNTON HAYCOCK; MORADI SHAYLI VARASTEH; THOMSON RAINE ELIZABETH STURT
权利人:Delica Therapeutics Pty Ltd
摘要:The present disclosure relates to polyphenols, including flavonoids, flavones and cannflavins, and methods of synthesising polyphenols. The present disclosure provides methods, enzymes and compositions that may be useful in the synthesis of polyphenols.

专利号:US-2024026314-A1
优先权日:2020-11-25
标题 :Polypeptides for use in the synthesis of bioactive phenolic compounds
发明人：ROTHSTEIN STEVEN; AKHTAR TARIQ; CASARETTO JOSE; PERRIN COLBY; VAN GELDER KRISTEN
权利人:ROTHSTEIN STEVEN; AKHTAR TARIQ; CASARETTO JOSE; PERRIN COLBY; VAN GELDER KRISTEN
摘要:Described herein is a polypeptide encoding a prenyltransferase for prenylating a polyphenol and a polypeptide encoding an O-methyltransferase for methylating a polyphenol. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or a polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or the polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a fragment of the polypeptide or the variant thereof.

专利号:US-2014357576-A1
优先权日:2013-05-31
标题:Methods for enhancement of muscle protein synthesis
发明人：BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
权利人:NESTEC SA
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

专利号:WO-2015040533-A1
优先权日:2013-09-19
标题:Methods for enhancing muscle protein synthesis during energy deficit
发明人：BAILEY DAVID MARK; ZALTAS ERIC SCOTT; STELLINGWERFF TRENT; MOORE DANIEL RYAN; HAWLEY JOHN ALAN; BURKE LOUISE MARY
权利人:PREMIER NUTRITION CORP
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis during periods of negative energy balance, or energy deficit. The methods include administering to an individual suffering from energy deficit a composition comprising protein in an amount from about 15 g to about 30 g during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof. The methods also include administering to an individual suffering from energy deficit a composition comprising protein during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof, wherein the protein is administered in a dose that is higher than doses typically recommended for individuals experiencing energy balance.

专利号:US-2014294788-A1
优先权日:2013-03-26
标 题 :Methods for enhancing muscle protein synthesis following concurrent training
发明人：BAILEY DAVID MARK; ZALTAS ERIC SCOTT; MOORE DANIEL RYAN; STELLINGWERFF TRENT
权利人:NESTEC SA
摘要:The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.

专利号:US-2019314312-A1
优先权日:2016-07-11
标题 :Combination therapy to increase endogenous nitric oxide (no) synthesis
发明人：EREZ AYELET; STETTNER NOA
权利人:YEDA RES & DEV
摘要:Provided are uses of a therapeutically effective amount of citrulline for the manufacture of a medicament for treatment of a subject having an inflammatory bowel disease (IBD) and/or colon cancer. Also provided are pharmaceutical compositions comprising a therapeutic effective amount of citrulline and a therapeutically effective amount of a flavonoid for the treatment of an inflammatory bowel disease (IBD) and/or colon cancer and kits comprising same.