CAS: 443-83-4; 2-Chloro-6-Fluorotoluene

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CAS号387-45-1 2-氯-6-氟苯甲醛 | CAS号87-60-5 3-氯-2-甲基苯胺 | CAS号95-52-3 邻氟甲苯 | CAS号446-55-9 3-chloro-2-meth... | CAS号55117-15-2 2-氯-6-氟氯苄 | CAS号387-45-1 2-氯-6-氟苯甲醛 | CAS号434-75-3 2-氯-6-氟苯甲酸 | CAS号392-22-3 2-氯-6-氟肉桂酸 | CAS号443-33-4 2-氯-6-氟苯甲醛肟 | CAS号625-98-9 间氯氟苯 | CAS号62476-62-4 α,α,2-三氯-6-氟甲苯 | CAS号68220-26-8 2-氯-6-氟溴苄 | CAS号185147-06-2 3-氟-2-甲基苯腈 | CAS号203302-92-5 3-溴-2-氯-6-氟甲苯

3-氯-2-甲基苯胺置于三氟化硼乙醚,亚硝酸异戊酯,四氟硼酸-二乙醚络合物体系中,用 四氢呋喃,全氟己烷 作为反应溶剂,化学反应 12.0H,反应生成 2-氯-6-氟甲苯
参考文献:通过使用氟化溶剂在固相载体和溶液中合成芳基氟化物
标题:通过使用氟化溶剂在固相载体和溶液中合成芳基氟化物
摘要:快速反应的f:全氟化溶剂c 6 F 14是balz-Schiemann反应新变体(用于合成氟化芳烃)的关键.在温和的条件下,将三氮烯在载体和溶液中转化为氟代芳烃(参见方案).该方法简便易行且价格便宜,并且可以产生以前难以制备的高纯度氟代芳烃.
DOI:10.1002/anie.201001507

专利信息

专利号:US-9771356-B2
优先权日:2012-09-21
标题 :Inhibitors of beta-hydroxylase for treatment of cancer
发明人：WANDS JACK R; DE LA MONTE SUZANNE; AIHARA ARIHIRO; OLSEN MARK JON; THOMAS JOHN-MICHAEL
权利人:RHODE ISLAND HOSPITAL; UNIV MIDWESTERN
摘要:The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel 2-aryl-5-amino-3(2H)-furanone and 2-heteroaryl-5-amino-3(2H)-furanone compounds, pharmaceutical compositions thereof, methods for their synthesis, and methods of using these compounds to modulate the activity of ASPH in an a cell-free sample, a cell-based assay, and in a subject. Other aspects of the invention relate to use of the compounds disclosed herein to ameliorate or treat cell proliferation disorders.

专利号:US-4369322-A
优先权日:1978-12-15
标 题 :Process for the production of substituted acetonitriles
发明人：SCHALKE PETER; KLEEMANN AXEL
权利人:DEGUSSA
摘要:The known synthesis for the production of aromatic substituted acetonitriles by reaction of aromatic substances with cyanogen chloride in the gas phase is improved by feeding the starting materials in gaseous form and separated from each other into the reactor. The process can be used to synthesize in general aromatic and especially hetero-aromatic substituted acetonitrile.

专利号:US-10270034-B2
优先权日:2014-05-26
标题 :Tetra-aryl indacenodithiophene-based polycyclic polymers and their use
发明人：MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID
权利人:MERCK PATENT GMBH
摘要:The present invention relates to compounds comprising a tetra-aryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.

专利号:US-9914742-B2
优先权日:2014-07-29
标 题 :Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use
发明人：MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID
权利人:MERCK PATENT GMBH
摘要:The present invention relates compounds comprising a tetra-heteroaryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.

专利号:US-9502658-B2
优先权日:2013-04-22
标题 :Fullerene derivatives and related materials, methods, and devices
发明人：JACKSON EDWARD A; RICHTER HENNING; BLOUIN NICOLAS; BERNY STÉPHANE
权利人:NANO-C INC; MERCK PATENT GMBH
摘要:The invention relates to improved fullerene derivatives, to methods for their synthesis and any educts or intermediates used in such methods, to compositions and formulations containing fullerene derivatives, to the use of the fullerene derivatives, compositions and formulations in, or for the preparation of, organic electronic (OE) devices like for example organic photovoltaic (OPV) devices or organic photodetectors (OPD), and to OE, OPV and OPD devices comprising, or being prepared from, these fullerene derivatives, compositions or formulations.

专利号:US-7825149-B2
优先权日:2006-01-19
标 题 :Substituted imidazoles
发明人：CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
权利人:PFIZER LTD
摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.