CAS: 382146-66-9; (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-3-(((2S,3R,4R,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-yl)Oxy)-5-Hydroxy-2-(((1S,2R,4Ar,6As,6Br,8Ar,10S,12Ar,12Br,14Ar,14Bs)-1-Hydroxy-1,6B,9,9,12A-Pentamethyl-2-(2-Methylprop-1-En-1-yl)Hexadecahydro-1H,6H-4A,6A-Methanonaphtho[1,2-H]Pyrano[2,3-C]Isochromen-10-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-4-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
- 英文名称(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-3-(((2S,3R,4R,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-yl)Oxy)-5-Hydroxy-2-(((1S,2R,4Ar,6As,6Br,8Ar,10S,12Ar,12Br,14Ar,14Bs)-1-Hydroxy-1,6B,9,9,12A-Pentamethyl-2-(2-Methylprop-1-En-1-yl)Hexadecahydro-1H,6H-4A,6A-Methanonaphtho[1,2-H]Pyrano[2,3-C]Isochromen-10-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-4-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
- 中文名称假马齿苋皂苷II
- IUPAC名称(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-3-(((2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-5-hydroxy-2-(((1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methylprop-1-en-1-yl)hexadecahydro-1H,6H-4a,6a-methanonaphtho[1,2-h]pyrano[2,3-c]isochromen-10-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- 其它别名Pseudojujubogenin 3-O-[α-L-Arabinofuranosyl-(1→2)-[β-D-Glucopyranosyl-(1→3)]-β-D-Glucopyranoside]; Bacopaside Ii(Sh); Bacopaside Ii(P); β-D-Glucopyranoside, (1S,2R,4Ar,6As,6Br,8Ar,10S,12Ar,12Br,14Ar,14Bs)-Hexadecahydro-1-Hydroxy-1,6B,9,9,12A-Pentamethyl-2-(2-Methyl-1-Propen-1-yl)-4A,6A-Methano-1H,6H-Phenanthro[2,1-D]Pyrano[2,3-B]Pyran-10-Yl O-α-L-Arabinofuranosyl-(1→2)-O-[β-D-Glucopyranosyl-(1→3)]-; Apoptosis,Bacopaside Ii,Inhibitor,Inhibit; Bacopaside Ii-Rm; Bacopaside Ii, 10 Mm In Dmso
- CAS编号382146-66-9
- MFCD编号:MFCD07779136
- FDA UNII编号:ZO6L404Y9T
- 分子式:C47H76O18分子量:929.11
- 产品CID: 1393490
- 产品分类生物化工 → 提取物 → 植物提取物
物理性质
合成工艺路线路线简述
海关参考信息
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主要参考文献
1: Anwar S, Mohammad T, Azhar MK, Fatima H, Alam A, Hasan GM, Islam A, Kaur P, Hassan MI. Investigating MARK4 inhibitory potential of Bacopaside II: Targeting Alzheimer's disease. Int J Biol Macromol. 2023 Jun
12:125364. doi: 10.1016/j.ijbiomac.2023.125364. Epub ahead of print. 19(3):653. doi: 10.3390/ijms19030653.
3: Tomita Y, Smith E, Palethorpe HM, Nakhjavani M, Yeo KKL, Townsend AR, Price TJ, Yool AJ, Hardingham JE. In Vitro Synergistic Inhibition of HT-29 Proliferation and 2H-11 and HUVEC Tubulogenesis by Bacopaside I and II Is Associated with Ca2+ Flux and Loss of Plasma Membrane Integrity. Pharmaceuticals (Basel). 2021 May 6;14(5):436. doi: 10.3390/ph14050436.
合成参考文献
参考文献:10.1248/cpb.54.907
摘要:Murthy PB, Raju VR, Ramakrisana T, Chakravarthy MS, Kumar KV, Kannababu S, Subbaraju GV. Estimation of twelve bacopa saponins in Bacopa monnieri extracts and formulations by high-performance liquid chromatography. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):907–11. doi: 10.1248/cpb.54.907.
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