CAS: 270263-04-2; (S)-3-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)Hex-5-Enoic Acid

该化合物是一种手性,受Fmoc保护的氨酸衍生物,具有末端烷基化合物组,其主要优点包括它作为固相合成(SPPS)的多功能构件的作用,能够通过点击化学或交叉相交反应将不饱和的侧链进一步功能化.Fmoc 组确保标准SPPS 协议的交替性,而(S) 配置在peptide 设计中保持立体化学完整性. 烷会允许合成后的修改, 如硫醇-反应或聚乙烯元体, 扩大其在生物合成和物质科学应用中的效用. 这种化合物对于将经过修改的peptide 与定制的特性合成特别有用.

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上下游产品

β-allyl aminopropionate (fluorenylmethoxy)carbonyl chloride

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    专利信息


    专利号:US-8598089-B2
    优先权日:2003-12-17
    标题 :Methods for synthesis of encoded libraries
    发明人：MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A
    权利人:MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A; GLAXOSMITHKLINE LLC
    摘要:The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

    专利号:US-8410028-B2
    优先权日:2003-12-17
    标 题:Methods for synthesis of encoded libraries
    发明人：MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A
    权利人:MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A; GLAXOSMITHKLINE LLC
    摘要:The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

    专利号:US-2007042401-A1
    优先权日:2003-12-17
    标题 :Methods for synthesis of encoded libraries

    专利号:US-2012245040-A1
    优先权日:2003-12-17
    标题 :Methods for synthesis of encoded libraries

    专利号:US-2009062147-A1
    优先权日:2003-12-17
    标 题:Methods for synthesis of encoded libraries

    专利号:US-7972994-B2
    优先权日:2003-12-17
    标 题 :Methods for synthesis of encoded libraries

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    合成参考文献

    合成方法参考DOI号:10.1016/j.bmcl.2008.07.074
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