CAS: 175204-46-3; 2,6-Dichloropyridine-4-Carbothioamide
该化合物是一种杂环化合物,在2和6个位置上以氯原子替代了核核心,在4个位置上以氯原子替代了碳二酰胺组.这种结构具有独特的反应性,使其成为有机合成中有价值的中间体,特别是用于开发药品,农用化学品和协调化学.电子提取氯原子和木二酰胺组的存在增强了其在核细胞替代和金属复合反应中的效用.在标准条件下,它的高纯度和稳定性确保了研究和工业应用的一贯性.该化合物的多功能性和定义明确的化学特性使得它成为专门合成途径的首选.
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上下游产品
CAS号32710-65-9 2,6-二氯-4-氰基吡啶合成工艺路线路线简述
📜2,6-二氯-4-氰基吡啶置于sodium Hydrogen Sulfide,Magnesium(II) Chloride Hexahydrate体系中,化学反应 2.0H,反应生成2,6-二氯吡啶-4-硫代酰胺
参考文献: Nuclear Transport Modulatiors And Uses Thereof[fr] Modulateurs De Transport Nucléaire Et Leurs Utilisations
标题: Nuclear Transport Modulatiors And Uses Thereof[fr] Modulateurs De Transport Nucléaire Et Leurs Utilisations
海关参考信息
- 2933310010-吡啶
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9550757-B2
优先权日:2010-03-05
标题:Nuclear transport modulators and uses thereof
发明人：SHACHAM SHARON; KAUFFMAN MICHAEL; SANDANAYAKA VINCENT P; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, pulmonary fibrosis, hepatic fibrosis, glomerulonephritis, and other renal disorders, and for the treatment of viral infections (both acute and chronic).
