CAS: 133-10-8; P-Aminosalicylic Acid Sodium Salt

该化合物是4-氨基硅酸的一种水溶性衍生物,通常用于制药和化学应用,其主要优点包括水溶性比母化合物高,便于液态或注射制剂的配制.芳香环上存在氨基和氢氧基基苯甲酸钠,有助于其发热特性,使其在协调化学方面有用.此外,在生理条件下的稳定性允许药物运载系统的潜在应用.该化合物的结构特征还表明作为有机合成中间体的效用,特别是衍生反应. 它与生物系统的兼容性进一步支持其在生物医学研究中的使用.

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65-49-6 65-49-6 6018-19-5

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ECHA物质ECHA物质C&L通报REACH预注册

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CAS号65-49-6 对氨基水杨酸 | CAS号65944-71-0 cytosinium 4-am... | CAS号50-86-2 4-乙酰氨基水杨酸 | CAS号14463-22-0 Benzoic acid,4-... | CAS号4323-00-6 Salicylic acid,... | CAS号50512-48-6 4-甲基丙烯酰胺基水杨酸 | CAS号20679-94-1 2-hydroxy-4-(ph... | CAS号96602-46-9 N-琥珀酰亚胺基4-氮杂水杨酸酯 | CAS号66761-27-1 4-叠氮水杨酸 | CAS号6945-11-5 Benzoicacid, 4-... | CAS号6935-15-5 2-hydroxy-4-phe... | CAS号6340-88-1 2-hydroxy-4-[(2...

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    专利信息


    专利号:US-2020054045-A1
    优先权日:2008-09-03
    标 题 :All-Natural Drink Composition for Synthesizing and Regenerating Adenosine Triphosphate (ATP) in Muscle Cells and Neurons, Repairing Exercise-Induced Muscle Fiber Damage, Repletion of Glycogen Stores in the Muscle and Liver, Enhancing Blood Flow to Tissue during Intense Exercise, and Preventing and Reducing Oxidative Damage to Tissues during Exercise with Minimal Gastrointestinal Disturbances
    发明人:SCHMIDT MICHAEL JAMES; AVARBOCK DAVID
    权利人:BIOMECHANICAL TECH LLC
    摘要:The present invention provides for a nutritional composition in a liquid drink form, dry powder form, gel form, or carrier form intended to optimize human physiological performance during intense exercise and subsequently return the body to its healthy, pre-exercise state. The composition comprises a carbohydrate and a protein, and preferably a ratio of the carbohydrate to the protein is greater than about 4.3 parts by weight carbohydrate to 1 part by weight protein. Preferably, the liquid nutritional composition is comprised of: (1) carbohydrate in the range of 3.45-10% by weight of the liquid nutritional composition to allow immediate and long-term energy production by muscle cells and neurons, insulin modulation, and muscle glycogen sparing, the carbohydrate being in the form of monosaccharides or polysaccharides or a combination thereof, and the saccharides preferably comprising 40-95% dextrose by weight of the final volume of saccharides, 5-45% fructose by weight of the final volume of saccharides, and 1-25% glucose polymer by weight of the final volume of saccharides; (2) a protein source that contains all 20 “standardâ€? amino acids, in the range of 0.1-0.8% by weight of the liquid nutritional composition, whose inherent structure plus further chemical modification results in amino acid absorption into the bloodstream rapid enough for initiating and enhancing protein synthesis and subsequent muscle cell repair during the exercise and post-exercise periods; (3) Branched-Chain Amino Acids (BCAA), leucine, isoleucine, valine, for use by muscle cells for energy thus sparing glycogen stores, for increasing protein synthesis by stimulating insulin and growth hormone release, and for reducing protein degradation; (4) precursors of the signaling molecule nitric oxide, important for increasing blood flow and subsequent nutrient delivery (including those in this composition) to tissue during intense exercise; (5) precursors of creatine, a molecule important for ATP regeneration in muscle and nerve cells and for muscle cell volumizing effects; (6) a mixture of hydrophilic and hydrophobic antioxidants: retinol/Beta-carotene (Vitamin A), ascorbic acid (Vitamin C), and di-alpha-tocopheryl acetate (Vitamin E); ubiquinone (coenzyme Q 10 [5-100 mg/500 ml], which in addition to its antioxidant properties is also important for ATP generation and Vitamin E regeneration; a mixture of 10-100 mg epigallocatechin gallate (EGCG) and 25-150 mg polyphenols from green tea extract; 40-250 mg ellagic acid and punicalagin from pomegranate or raspberry extract, at ratios comparable to that found in the whole fruit, which have been shown to have protective effects on blood vessels as well as inhibiting stimulation of the pro-inflammatory protein interleukin-1 b (IL-b) which causes degradation and damage to joints (These six antioxidants prevent and eradicate reactive oxygen species and free radicals generated during strenuous exercise, thus preserving muscle integrity.); and (7) the ions Na+, Cl−, K+, Ca+2, Mg+ 2 , and Zn+ 2 , which are important for the muscle fiber contraction and relaxation cycle, for neuronal signal propagation, for repletion of such ions lost in excessive perspiration during exercise, for water absorption in the gastrointestinal tract, and for catalytic action by energy producing and antioxidant enzymes.

    专利号:US-7989004-B2
    优先权日:2004-05-27
    标题:Antitubercular extracts of Salicornia brachiata
    发明人:RATHOD MEENA RAJNIKANT; SHETHIA BHUPENDRA DHANVANTRAI; PANDYA JAYANT BATUKRAL; GHOSH PUSHPITO KUMAR; DODIA PRAKASH JAGIVANBHAL; SRIVASTAVA BRAHM S; SRIVASTAVA RANJANA; SRIVASTAVA ANIL; CHATURVEDI VINITA; VAIRAMANI MARIAPPANADAR
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from Salicornia brachiata . The invention also discloses the non-toxic nature of the fraction and positively identifies Sucrose as its main constituent. Pure Sucrose is shown to have no anti-tubercular activity indicating thereby that activity of the fraction resides in one or more of the minor constituents. The minor constituents are shown to be relatively low molecular weight entities and a chromatographic technique is disclosed for separating them from the bulk sucrose to probe their activities and structures in detail, as also the possibility of their synthesis if the leads thrown up are novel.

    专利号:US-6051236-A
    优先权日:1998-11-12
    标题 :Composition for optimizing muscle performance during exercise
    发明人:PORTMAN ROBERT
    权利人:PACIFICHEALTH LAB INC
    摘要:A nutritional composition in a dry powder form for optimizing muscle performance during exercise and for enhancing muscle cell repair and recovery following the cessation of exercise. The dry nutritional composition includes carbohydrates and proteins in a ratio in the range of 2.8 to 4.2 parts of the carbohydrates to 1.0 part of the proteins, wherein the carbohydrates are used for providing energy during exercise and the proteins are used for stimulating the release of insulin to the muscle cells during exercise and for repairing muscle cells after exercise. The dry nutritional composition further includes glutamine for reducing muscle stress by stimulating the immune system and for stimulating muscle cell recovery after exercise; arginine for stimulating the release of insulin within the muscle cells in order to facilitate the transport of glucose into the muscle cells during exercise and for the synthesis of glucose into glycogen; vitamin C for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise; and vitamin E for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise. Additionally, the dry nutritional composition also includes one or more electrolytes for replenishing electrolytes lost during exercise and for facilitating intestinal reabsorption of fluids, and for facilitating energy dependent processes; and an herbal compound being ciwujia for enhancing the immune system, reducing muscle stress, and decreasing heart rate during exercise.

    专利号:JP-2013234166-A
    优先权日:2012-05-09
    标 题 :Synthesis of phenylacetic acid by carbonylation of toluene

    专利号:CH-651317-A5
    优先权日:1978-07-28
    标题 :METHOD FOR ENZYMATIC SYNTHESIS OF DOUBLE-STRAND RNA, THIS METHOD, SYNTHETIZED DOUBLE-STRING RNA AND INTERFERON INDUCTORS CONTAINING THEM.

    专利号:US-2007148246-A1
    优先权日:2005-08-11
    标题:Nucleic Acid-Based Matrixes
    发明人:LUO DAN; LI YOUGEN
    权利人:LUO DAN; LI YOUGEN
    摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.
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    合成参考文献


    摘要:Yaoxue Tongbao. Bulletin of Pharmacology., 15(12)(17), 1980
    摘要:Dissertationes Pharmaceuticae et Pharmacologicae., 23(383), 1971
    摘要:Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie., 6B(183), 1951
    参考文献:10.1007/bf00290533
    摘要:Wechser MA, Bowman BJ. Regulation of the expression of three housekeeping genes encoding subunits of the Neurospora crassa vacuolar ATPase. Molecular Genetics and Genomics. 1995 May;249(3):317–27. doi: 10.1007/bf00290533.
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