CAS: 109-04-6; 2-Bromopyridine

上下游产品

CAS号624-28-2 2,5-二溴吡啶 | CAS号96-22-0 3-戊酮 | CAS号626-05-1 2,6-二溴吡啶 | CAS号14305-17-0 2-溴吡啶-N-氧化物 | CAS号142-08-5 2-羟基吡啶 | CAS号504-29-0 2-氨基吡啶 | CAS号80866-91-7 2-溴吡啶 N-氧化物盐酸盐 | CAS号110-86-1 吡啶 | CAS号109-09-1 2-氯吡啶 | CAS号65007-00-3 三氟甲基磺酸-2-吡啶基酯 | CAS号106308-26-3 1,2-双(二-2-吡啶基膦)乙烷 | CAS号111759-97-8 2-pyridin-2-ylp... | CAS号110225-73-5 3-(2-吡啶)环己酮 | CAS号109660-12-0 2-(4,5-二氢-4,4-二... | CAS号366-18-7 2,2'-联吡啶 | CAS号4411-80-7 6,6′-二甲基-2,2′-联吡啶 | CAS号56100-22-2 6-甲基-2,2'-联吡啶 | CAS号32111-34-5 4-(2-吡啶基)苯甲腈 | CAS号34803-66-2 1-(2-吡啶基)哌嗪 | CAS号3430-17-9 2-溴-3-甲基吡啶

2-吡啶甲酸置于次氯酸叔丁酯,二氯甲烷,氧气,碳酸氢钠体系中,化学反应 20.0H,以65%的收率获得2-溴吡啶
参考文献:在氧条件下用2-卤代甲烷对2-吡啶甲酸进行无过渡金属的脱羧卤化作用†
标题:在氧条件下用2-卤代甲烷对2-吡啶甲酸进行无过渡金属的脱羧卤化作用†
摘要:描述了一种方便有效的合成2-卤素取代的吡啶的方法.经由n-氯卡宾中间体使2-吡啶甲酸与二卤代甲烷的脱羧卤化反应顺利进行,以令人满意的收率在无过渡金属的条件下提供2-卤素取代的吡啶.这种新型的脱羧卤化反应操作简单,并且具有很高的官能团耐受性.
Doi:10.1039/c9Gc02407G

专利信息

专利号:US-9755163-B2
优先权日:2010-04-30
标 题:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof
发明人：LI JIAN; TURNER ERIC
权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV; ARIZONA BOARD OF REGENTS ACTING FOR OR ON BEHALF OF ARIZONA STATE UNIV
摘要:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.

专利号:US-4749806-A
优先权日:1984-12-28
标题:Process for the synthesis of isocyanates and of isocyanate derivatives
发明人：TKATCHENKO IGOR; JAOUHARI RABIH; BONNET MICHEL; DAWKINS GORDON; LECOLIER SERGE
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:The present invention relates to a process for the synthesis of isocyanates and of isocyanate derivatives. Isocyanates are obtained by reacting an organic halide with a metal cyanate in an organic medium in the presence of a catalyst consisting of a complex of nickel with at least one organic ligand, in which complex the nickel is in the zero oxidation state. A carbamate or a urea, respectively, are obtained by a subsequent reaction with a hydroxy compound or a primary or secondary amine. Isocyanates and their derivatives are used especially either as refined synthesis agents for the production of pesticides and medications, or as monomers or comonomers for the preparation of many macromolecular compounds.

专利号:US-2023174567-A1
优先权日:2020-05-22
标题:Synthesis of fluorinated nucleotides
发明人：ARMIGER TRAVIS; BELYK KEVIN M; BENKOVICS TAMAS; CHUNG CHEOL K; JI CHEN YINING; JOHNSON HEATHER CLAIRE; KLAPARS ARTIS; LIU ZHIJIAN; LIU ZHUQING; MOORE JEFFREY C; NEEL ANDREW J; PENG FENG; RUMMELT STEPHAN M; SALEHI MARZUARANI NASTARAN; SHERRY BENJAMIN D; SONG ZHIGUO JAKE; TURNBULL BEN WILLIAM HULME; WANG LU; XU FENG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (2S,3R,4S,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-fluoro-4-hydroxy-2-(mercaptomethyl)tetrahydrofuran-3-yl dihydrogen phosphate, also known as 3′-fluoro-thio-guanosine monophosphate or 3′-F-thio-GMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation. (I)

专利号:US-8697876-B2
优先权日:2010-04-02
标 题:Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
发明人：CARNIAUX JEAN-FRANCOIS; CUMMINS JONATHAN
权利人:CARNIAUX JEAN-FRANCOIS; CUMMINS JONATHAN; COLUCID PHARMACEUTICALS INC
摘要:The present invention provides a novel polymorph of the hemisuccinate salt of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide (Form A) characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well as a unique crystalline structure. This polymorph is useful in pharmaceutical compositions, for example, for the treatment and prevention of migraine. The invention also provides a process for the synthesis of pyridinoylpiperidine compounds of Formula I in high yield and high purity. In particular, the provides a process for the preparation of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide, its hemisuccinate salt and polymorph (Form A).

专利号:US-9926291-B2
优先权日:2007-03-27
标 题 :Synthesis of thiohydantoins
发明人：OUERFELLI OUATHEK; DILHAS ANNA; YANG GUANGBIN; ZHAO HONG
权利人:SLOAN KETTERING INST CANCER RES
摘要:A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.

专利号:US-11447454-B2
优先权日:2015-08-07
标题:Synthesis of benzodiazepine derivatives
发明人：BOYCE MALCOLM JAMES; THOMSEN LIV; GILBERT DONALD ALAN; WOOD DAVID
权利人:TRIO MEDICINES LTD
摘要:The invention relates to processes for the synthesis of benzodiazepine derivatives of Formula I: