CAS: 9001-33-6; ((Fluoro-L3-Iodaneylidene)Methyl)-L3-Iodanimine

该化合物是细胞蛋白家族的蛋白酶. 它具有广泛的基质特性,有效的水解蛋白,和薄膜等温和条件. Fisin因其在pH水平(4-9.0) 和温度方面的稳定性而受到重视,因此适合生物化学,食品加工和工业蛋白降解等多种应用. 它的水溶剂和有机溶剂的高活性进一步增强了其在专门酶反应中的效用. Fisinin的自然起源和强力催化特性将它定位为需要精确蛋白修改的研究和工业过程的多功能工具.

结构式图片

欧盟法规

统一分类与标签ECHA物质ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

合成工艺路线路线简述

    专利信息


    专利号:US-11116810-B2
    优先权日:2012-10-26
    标 题 :Methods for treatment of skin and skin appendages with a linseed extract as an active agent activating the synthesis of antimicrobial peptides
    发明人:BOTTO JEAN-MARIE; DOMLOGE NOUHA; PORTOLAN FREDERIQUE
    权利人:ISP INVESTMENTS INC; ISP INVESTMENTS LLC
    摘要:Methods for the treatment of irritations of the skin and skin appendages caused by microbial stresses are disclosed. The methods include providing a composition comprising a linseed extract, obtained from hydrolysis of linseed proteins, as an active antimicrobial agent in a physiologically acceptable medium, and topically applying the linseed extract onto the skin in need thereof. The methods may be useful in the cosmetic and pharmaceutical field and, more particularly, in the field of dermatology. Cosmetic methods for reinforcing the chemical barrier function of healthy and/or sensitive skin and skin appendages are also disclosed that include the same or similar composition and steps.

    专利号:US-4389489-A
    优先权日:1979-07-07
    标 题:Optically pure heterocyclic aminoacid compounds, a process for their use for the synthesis of medicaments
    发明人:PREISS MICHAEL; SCHUTT HERMANN
    权利人:BAYER AG
    摘要:The invention relates to optically pure heterocyclic amino acid compounds of the Formula I, as described hereinabove as well as a process for their preparation involving subject D, L-compounds to the action of a proteolytic enzyme. The compounds obtained are useful, inter alia, as intermediates for the manufacture of cephalosporins or penicillins.

    专利号:US-2012282652-A1
    优先权日:2011-02-28
    标题 :Preparation of peptide mixtures by protease catalysis designed to provide useful biological and physical properties
    发明人:GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU
    权利人:GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU; POLITECHNIC INST UNIV NEW YORK
    摘要:A process for preparing unique peptide mixtures with a broad range of uses using combinations of natural and non-natural amino acid alkyl ester monomers and specific combinations of these monomers as dimers, trimers and higher oligomers selected from the large group of structural motifs that lead to useful physical and/or biological properties and that have been or may be identified from solid state peptide synthesis, isolation of peptides from natural sources, and production of peptides by recombinant DNA methods, or identification of peptides by recombinant methods such as phage display, the method of peptide synthesis comprising a) admixing one or more natural and non-natural amino acid alkyl ester monomer, dimer, trimer and higher oligomers with one or more proteases in a reaction medium; b) heating the mixture to between about 5° C. to about 90° C. for between 5 minutes and 24 hours; and c) recovering the formed oligopeptide.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-8658218-B2
    优先权日:1999-08-17
    标 题 :Composition with anti-inflammatory, protein synthesizing, treatment of enzyme deficiency, activating genetic therapy and anti-cancer activity and methods of use
    发明人:GIRSH LEONARD S
    权利人:GIRSH LEONARD S; IMMUNOPATH PROFILE INC
    摘要:A composition for treating damaged tissue and promoting healthy tissue growth, healing and tissue regeneration, wherein the composition comprises an extracellular matrix compound, a surface-active lipid, one or more enantiomericaily pure L-amino acids or glycine, a hydrophilic surfactant with a high HLB, as well as vitamins, minerals or trace elements. Not only does it maintain good health, but the components are non-intrusive, bio-safe, non-coalescent and can mimic normally occurring stem-cells within a body. When applied to diseased tissues, the subject compositions can stimulate, facilitate, and accelerate protein synthesis for the regeneration of diseased organs and tissues. The healing efficacy of these tissue components gives us further appreciation of the protective action of human tissue over and above and other than the immune protective system or perhaps an integral component part of the immune system.

    专利号:US-2006252134-A1
    优先权日:1999-10-29
    标 题 :Enantioselective oligomerization of alpha-hydroxy carboxylic acids and alpha-amino acids
    发明人:LORBERT STEVE; SCHASTEEN CHARLES S; URAIZEE FAROOQ; KAPILA SHUBHENDER
    权利人:NOVUS INT INC
    摘要:An enzymatic synthesis and composition of oligomers and co-oligomers comprised of α-hydroxy carboxylic acids and α-amino acids or peptides is disclosed. In a preferred embodiment, a α-hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a α-amino acid specific with a specific chiral configuration or linked by an amide linkage to a peptide made up of α-amino acid monomers having identical chiral configurations. Proteolytic enzymes catalyze oligomerization of the α-hydroxy carboxylic acid and α-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to animals such as ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen and other animals such as swine, poultry and aquatic animals.

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