CAS: 82467-50-3; 2,3,13-Trimethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-1-Ol

该化合物是主要源于Schisandra中国人植物的果实的离子体化合物,以其传统用途而闻名于草药中,它展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的...

英文名称2,3,13-Trimethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-1-Ol
中文名称R(+)-戈米辛 M1
IUPAC名称2,3,13-trimethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-1-ol
其它别名R(+)-Gomisin M1; Gomisin M; Benzo[3,4]Cycloocta[1,2-F][1,3]Benzodioxol-1-Ol,5,6,7,8-Tetrahydro-2,3,13-Trimethoxy-6,7-Dimethyl-, (6R,7S,13Ar)-Rel-
CAS编号82467-50-3
MFCD编号:MFCD20260383
分子式:C22H26O6分子量:386.44
产品CID: 1815398
产品分类有机原料 → 苯丙烷和聚酮 → 单宁

相似结构搜索
产品信息参考;;;;
InChIKey: OGJPBGDUYKEQLA-UHFFFAOYNA-N
InChI=1S/C22H26O6/c1-11-6-13-8-15(24-3)20(25-4)19(23)17(13)18-14(7-12(11)2)9-16-21(22(18)26-5)28-10-27-16/h8-9,11-12,23H,6-7,10H2,1-5H3
计算化学: 氢键受体数6.0氢键供体数1.0可旋转键数3.0

物理性质

沸点568.6±50.0 °C(预测)
闪点297.7±30.1 °C
密度1.195±0.06 g/cm3(预测)
pKa:8.96±0.60(预测)
PSA:66.38
LogP:4.1845
溶解性Soluble In Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,Etc.
外观形态白色至类白色粉末
产品应用该化合物是一种有力的抗艾滋病毒剂,其EC50 < 0.65 ΜM.

MSDS等安全信息

危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
防范说明P264+P280+P305+P351+P338+P337+P313
安全声明H303+H313+H333

上下游产品

24H28O7C24H28O7(+/-)-gomisin and (+/-)-γ-schizandrin gomisin N

合成工艺路线路线简述

📜Acetyl-Binankadsurin A置于lithium Aluminium Tetrahydride,三氯化铝体系中,用乙醚作为反应溶剂,以12 Mg的收率获得产物五味子酚 B
参考文献:Schisantherins Lo And Acetylschisantherin L From Kadsura Coccinea
标题:Schisantherins Lo And Acetylschisantherin L From Kadsura Coccinea
摘要:Five New Lignans,Schisantherins L-0 And Acetylschisantherin L,Were Isolated From The Seeds Of Kadsura Coccinea. Their Structures,Including Absolute Configurations,Were Elucidated By Spectroscopic Analysis And Chemical Conversions.
DOI:10.1016/s0031-9422(00)95108-2