CAS: 823-86-9; N-(4-Chlorophenyl)Hydroxylamine

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CAS号100-00-5 对硝基氯苯 | CAS号116278-63-8 N-(4-chlorophen... | CAS号109-89-7 二乙胺 | CAS号106-47-8 对氯苯胺 | CAS号932-98-9 1-chloro-4-nitr... | CAS号1503-91-9 Acetamide,N-(4-... | CAS号51639-68-0 N-(4-chlorophen... | CAS号1528-82-1 N-(4-Chlorophen... | CAS号932-98-9 1-chloro-4-nitr... | CAS号100-01-6 对硝基苯胺 | CAS号10569-67-2 [1,1':2',1''-Te... | CAS号63344-48-9 [1,1':3',1''-三联... | CAS号92-67-1 4-氨基联苯 | CAS号73006-78-7 5-氯[1,1'-联苯]-2-胺 | CAS号19865-61-3 chlofenamic acid | CAS号22861-52-5 N-(4-chlorophen... | CAS号19865-60-2 N-(4-Chlorophen... | CAS号22072-89-5 5-氯-3-苯基-1H-吲哚

📜对硝基氯苯置于rh On Carbon 肼体系中,用 四氢呋喃 作为反应溶剂,化学反应生成 4-氯苯基羟胺
参考文献:S-(n-芳基-N-羟基氨基甲酰基)谷胱甘肽衍生物是乙二醛酶i的紧密结合抑制剂和乙二醛酶ii的慢底物.
标题:S-(n-芳基-N-羟基氨基甲酰基)谷胱甘肽衍生物是乙二醛酶i的紧密结合抑制剂和乙二醛酶ii的慢底物.
摘要:S-(n-芳基-N-羟基氨基甲酰基)谷胱甘肽衍生物是抗癌目标酶乙二醛酶i的强大竞争性抑制剂.确实,Np-溴苯基衍生物是人类红细胞中最强的酶抑制剂,据报道(ki = 1.4 X 10 (-8)m).结构活性的相关性表明,该衍生物对人和酵母乙二醛酶i的亲和力高是由于该衍生物是与乙二醛酶i反应相关的烯二醇(酸酯)中间体的疏水类似物.衍生物也被证明是硫酯水解酶乙二醛酶ii(牛肝)的慢底物.基于某些类型的癌细胞中乙二醛酶ii活性异常低的水平,这类化合物作为潜在的肿瘤选择性抗癌剂受到关注.
DOI:10.1021/jm00040A007

专利信息

专利号:US-2024216893-A1
优先权日:2021-04-21
标题 :Hydrogenation catalyst, flow-type organic synthesis system using the same, and manufacturing method of hydrogenated organic compound
发明人：KADO SHIGERU; WATANABE TOSHIYUKI; KIRYU ASAKO
权利人:CHIYODA CORP
摘要:[Task] The task is to improve, in the hydrogenation of an aromatic halonitro compound, the yield of halogenated aromatic amine as a target product without the need for a dehalogenation inhibitor while suppressing the production of a nitroso compound. n [Solution] A hydrogenation catalyst for hydrogenation of an aromatic halonitro compound includes: a carrier containing at least one of silica, titania, and alumina; and at least one metal carried by the carrier and selected from group 10 elements in a periodic table.

专利号:WO-2024018965-A1
优先权日:2022-07-21
标 题 :Hydrogenation catalyst, and flow-type organic synthesis system and method for producing hydrogenated organic compound using same
发明人：KADO SHIGERU; WATANABE TOSHIYUKI; KIRYU ASAKO; MAEDA Kyogo
权利人:CHIYODA CORP
摘要:[Problem] To suppress any reduction in the selectivity of halogenated aromatic amines of a target product caused by a halogen separation reaction in hydrogenation of an aromatic halonitro compound. [Solution] A hydrogenation catalyst that is used in hydrogenating an aromatic halonitro compound, wherein the hydrogenation catalyst is configured to contain a carrier that contains at least one of titania and alumina, and palladium that is supported on the carrier, the average particle diameter of the palladium being 9.7 nm or less.

专利号:DE-3604051-A1
优先权日:1986-02-08
标 题:NEW 0- (DIPHENYLPHOSPHINYL) HYDROXYLAMINE, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE SYNTHESIS OF HYDRAZINE DERIVATIVES

专利号:CN-1093705-A
优先权日:1992-09-14
标 题 :Synthesis of novel diaryl-substituted 1,3-oxathia-1,3-dithia- and 1,3-dioxolanes and their therapeutic applications

专利号:CN-114426510-B
优先权日:2022-02-18
标题 :A kind of synthesis method of fully substituted β-lactam

专利号:CN-113929605-B
优先权日:2021-11-12
标题:A kind of ortho-sulfonylated arylamine compound and its synthesis method