CAS: 7779-77-3; Isobutyl 2-Aminobenzoate

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CAS号32357-18-9 2-nitro-benzoic... | CAS号78-83-1 异丁醇 | CAS号118-92-3 邻氨基苯甲酸 | CAS号118-48-9 靛红酸酐

📜2-Nitro-Benzoic Acid Isobutyl Ester置于platinum(Iv) Oxide,氢气体系中,用 Various Solvent(S) 作为反应溶剂,以86.3%的收率获得产物2-氨基苯甲酸异丁酯
参考文献:Steric Effects In Acid-Catalyzed Decomposition And Base-Catalyzed Cyclization Of 1-(2-Alkoxycarbonylphenyl)-3-Phenyltriazenes
标题:Steric Effects In Acid-Catalyzed Decomposition And Base-Catalyzed Cyclization Of 1-(2-Alkoxycarbonylphenyl)-3-Phenyltriazenes
摘要:已合成了1-(2-烷氧羰基苯基)-3-苯基三氮烯的八种衍生物(r = 甲基,乙基,丙基,异丙基,丁基,异丁基,己基和烯丙基),并测量了它们的紫外-可见,红外,^1H和^13C核磁共振光谱.详细解释了核磁共振光谱.在25.0oc的52.1% W/w甲醇中测定了这些化合物的酸催化分解和碱催化环化的动力学.验证了单位反应阶数,并鉴定了环化产物.利用得到的ph-曲线计算了所有衍生物的酸催化分解催化速率常数ka和碱催化环化催化速率常数kb;这些常数已根据归纳和空间效应进行了解释.发现酸催化分解催化速率常数ka与取代基无关.碱催化环化催化速率常数kb在统计上显著取决于归纳和空间效应,对前者的敏感性更显著.实验结果及其解释证实了碱催化环化机制,形成四面体中间体作为速率限制步骤.
DOI:10.1135/cccc19960751

专利信息

专利号:US-4042600-A
优先权日:1972-10-17
标 题 :Pyrolysis of 2-sulfochloride benzoates
发明人：DIPIPPO CARMINE A
权利人:SCOTT PAPER CO
摘要:Ortho-sulfobenzoic anhydride is synthesized by pyrolysis of the 2-sulfochloride benzoates. The benzoate intermediates are readily prepared by reacting either the esters of dithiodibenzoic acid with chloride water or the 2-diazonium chloride benzoates with sulfur dioxide. The invention also provides for the total synthesis of saccharin, free of bitter tasting contaminants, from such reactants, the ultimate step in such synthesis being the ammonolysis of the o-sulfobenzoic anhydride.

专利号:US-4259499-A
优先权日:1972-10-17
标 题:Method for preparing 2-sulfochloride benzoates and the use of same in the preparation of saccharin
发明人：DIPIPPO CARMINE A
权利人:JAMES RIVER GRAPHICS INC
摘要:A method of preparing 2-sulfochloride benzoates which comprises diazotizing any anthranilate to form a 2-diazonium chloride benzoate and thereafter reacting said 2-diazonium chloride benzoate with sulfur dioxide to form a 2-sulfochloride benzoate. The invention also provides for the total synthesis of saccharin which comprises pyrolyzing a 2-sulfochloride benzoate to form an o-sulfobenzoic anhydride and then ammonolyzing the o-sulfobenzoic anhydride to saccharin which is free of bitter tasting contaminants from such reactants.

专利号:WO-2025073852-A2
优先权日:2023-10-03
标 题:Enzymatic synthesis of glycosylated anthranilate derivatives