CAS: 73033-09-7; Cis-10-Nonadecenoic Acid

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3-Methylsulfanyl-5-((Z)-°Ctadec-9-enyl)-1,4-diphenyl-4H-[1,2,4]triazol-1-ium; iodide Oleic aldehyde10(E)-nonadecenoic acid

📜1,10-癸二醇置于chromium(Vi) Oxide,硫酸,水,氢溴酸,Sodium Hexamethyldisilazane体系中,用 四氢呋喃,丙酮,甲苯 作为反应溶剂,化学反应 77.0H,反应生成 10-十九碳烯酸
参考文献:Design,Synthesis And Antimycobacterial Activities Of 1-Methyl-2-Alkenyl-4(1H)-Quinolones
标题:Design,Synthesis And Antimycobacterial Activities Of 1-Methyl-2-Alkenyl-4(1H)-Quinolones
摘要:A Series Of 23 New 1-Methyl-2-Alkenyl-4(1H)Quinolones Have Been Synthesized And Evaluated In Vitro For Their Antimycobacterial Activities Against Fast Growing Species Of Mycobacteria,Such As Mycobacterium Fortuitum,M. Smegmatis And M. Phlei. The Compounds Displayed Good To Excellent Inhibition Of The Growth Of The Mycobacterial Test Strains With Improved Antimycobacterial Activity Compared To The Hit Compound,Evocarpine. The Most Active Compounds,Which Possessed Chain Length Of 11-13 Carbons At Position-2 Displayed Potent Inhibitory Effects With An Mic Value Of 1.0 Mg/l. In A Human Diploid Embryonic Lung Cell Line,Mrc-5 Cytotoxicity Assay,The Alkaloids Showed Weak To Moderate Cytotoxic Activity. Biological Evaluation Of These Evocarpine Analogues On The Less Pathogenic Fast Growing Strains Of Mycobacteria Showed An Interesting Antimycobacterial Profile And Provided Significant Insight Into The Structure-Activity Relationships. (C) 2010 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmc.2010.10.060