专利号:US-7718578-B2 优先权日:2003-03-31 标 题 :Method of synthesis and testing of combinatorial libraries using microcapsules 发明人:GRIFFITHS ANDREW DAVID; ABELL CHRIS; HOLLFELDER FLORIAN; MASTROBATTISTA ENRICO 权利人:MEDICAL RES COUNCIL 摘要:The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalizing two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalized into the microcapsules.
专利号:US-12006540-B2 优先权日:2015-09-28 标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis 发明人:JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J 权利人:UNIV COLUMBIA 摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.
专利号:US-2009169921-A1 优先权日:2008-01-02 标题 :Synthesis of triphenylene and pyrene based aromatics and their application in oleds 发明人:CHENG CHIEN-HONG; LIN CHANG-SHENG 权利人:CHENG CHIEN-HONG; LIN CHANG-SHENG 摘要:The present invention provides a compound of the general formula n Ar 1 —R 1 —Ar 2   (I) n wherein Ar 1 and Ar 2 independently represent triphenylenyl or pyrenyl, and R 1 represent a bond, aryl, or heteroaryl. The present invention also provides a process for the preparation of the compound formula (â–¡), and an organic electroluminescence device utilizing luminescent material comprising the compound of formula (â–¡) as an emitting layer.
专利号:US-6288221-B1 优先权日:1998-08-20 标 题 :Methods of synthesis of halogen base-modified oligonucleotides and subsequent labeling with a metal-catalyzed reaction 发明人:GRINSTAFF MARK W; BEILSTEIN AMY E; KHAN SHOEB I 权利人:UNIV DUKE 摘要:The present invention provides metal-containing purines, pyrimidines, nucleosides, nucleotides and oligonucleotides; including phosphoramidite and photolabile derivatives thereof, including methods of making and method of using same. The present invention provides a method for detection of nucleic acid sequences via electrochemical or photochemical means.
专利号:EP-1760080-A1 优先权日:2000-08-17 标 题:Design and synthesis of thiophene derived NLO materials for electro-optic applications 发明人:LONDERGAN TIM; TODOROVA GALINA K; ZHU JINGSONG; HUANG DIYUN 权利人:LUMERA CORP 摘要:In various embodiments, chromophores are described that include novel electron acceptors, novel electron donors, and/or novel conjugated bridges that are useful in nonlinear optical applications. In some embodiments, the present invention provides chromophore architectures wherein a chromophore contains more than one electron acceptor in electronic communication with a single electron donor, and/or more than one electron donor in electronic communication with a single electron acceptor. Also described are processes for providing materials comprising the novel chromophores and polymer matrices containing the novel chromophores. Electro-optic devices described herein contain one or more of the described electron acceptors, electron donors, conjugated bridges, or chromophores.
专利号:US-11959137-B2 优先权日:2015-09-28 标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
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