专利号:US-2007167530-A1 优先权日:2003-12-23 标 题:Method for depletion of sulphur and/or compounds containing sulphur from a biochemically produced organic compound 发明人:GERLACH TILL; MELDER JOHANN-PETER; HOFFER BRAM W; MEIER ANTON 权利人:BASF AG 摘要:Method of reducing the concentration of sulfur and/or a sulfur-containing compound in a biochemically prepared organic compound by bringing the respective organic compound into contact with an adsorbent. Ethanol which has a particular specification and can be prepared by the abovementioned method, and its use as solvent, disinfectant, as component in pharmaceutical or cosmetic products or in foodstuffs or in cleaners, as feed in steam reforming processes for the synthesis of hydrogen or in fuel cells, or as building block in chemical synthesis.
专利号:US-6608196-B2 优先权日:2001-05-03 标题 :Process for solid supported synthesis of pyruvate-derived compounds 发明人:WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L 权利人:GALILEO PHARMACEUTICALS INC 摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.
专利号:US-5637757-A 优先权日:1995-04-11 标 题 :One-pot synthesis of ring-brominated benzoate compounds 发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH 权利人:GREAT LAKES CHEMICAL CORP 摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.
专利号:US-2024109894-A1 优先权日:2019-10-30 标 题:Synthesis of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2-yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one
专利号:US-8633182-B2 优先权日:2012-05-30 标题:Indanyloxyphenylcyclopropanecarboxylic acids 发明人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN 权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT 摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
专利号:US-6809202-B2 优先权日:1996-11-07 标 题 :Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof 发明人:NEFZI ADEL; OSTRESH JOHN M; HOUGHTEN RICHARD A 权利人:TORREY PINES INST 摘要:The synthesis of individual di- and tri-substituted-1,4-diazacyclic compounds having 6- to 8-atoms in the cyclic ring, their corresponding 1,6-diketo-2,5-diazacyclic compounds and similar 1,4-diazacyclic ring compounds having one ring carbonyl gorup and 6-8 atoms in the ring is disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.
[参考文献]: Jiancai Zhu, Et Al. Comparison Of Aroma-Active Volatiles In Oolong Tea Infusions Using Gc-Olfactometry, Gc-Fpd, And Gc-Ms. J Agric Food Chem. 2015 Sep 2;63(34):7499-510.
合成参考文献
参考文献:10.1007/s10482-011-9622-x 摘要:Valle-Rodríguez JO, Hernández-Cortés G, Córdova J, Estarrón-Espinosa M, Díaz-Montaño DM. Fermentation of Agave tequilana juice by Kloeckera africana: influence of amino-acid supplementations. Antonie Van Leeuwenhoek. 2012 Feb;101(2):195–204. doi: 10.1007/s10482-011-9622-x.