CAS: 4461-30-7; Chloroacetyl Isocyanate

📜Silver Cyanate,氯乙酰胺 以 乙醚 作为反应溶剂,化学反应生成 氯乙酰异氰酸酯
参考文献:Naito; Nakagawa; Okumura,Journal Of Antibiotics,1965,Vol. 18,# 4,P. 145-157
标题:Naito; Nakagawa; Okumura,Journal Of Antibiotics,1965,Vol. 18,# 4,P. 145-157

专利信息

专利号:US-4502994-A
优先权日:1982-12-09
标题 :Enantiomeric synthesis of 3-amino-4-carbamoyloxymethyl-2-azetidonone-1-sulfate
发明人：WEI CHUNG-CHEN; WEIGELE MANFRED
权利人:HOFFMANN LA ROCHE
摘要:A novel enantiomeric synthesis from ascorbic acid of (3S,4S)-3-amino-4-carbamoyloxymethyl-2-azetidinone-1-sulfate, an intermediate for an antibiotic compound.

专利号:US-9265773-B2
优先权日:2011-09-08
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI; MERCK SHARP & DOHME; MSD ITALIA SRL
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-5202459-A
优先权日:1989-11-07
标题 :Process for producing cyclobutane derivative
发明人：KANEKO CHIKARA; KATAGIRI NOBUYA
权利人:NIPPON KAYAKU KK
摘要:The present invention relates to a process for producing cyclobutane derivatives represented by general formula (28): ##STR1## (wherein R represents a substituent; R 2 represents an electron attracting group and Nu represents a substituent corresponding to nucleophilic reagent), by reacting a compound represented by general formula (27): ##STR2## (wherein R has the same significance as defined above and R 1 represents an electron attracting group) with nucleophilic reagents Nu.sup.⊖ in a solvent. n The compounds of formula (28) are useful as intermediates for synthesis of, for example, 9-[2,3-bis(hydroxymethyl)cyclobutan-1-yl]guanine which is expected to be useful as an antiviral agent.