CAS: 4299-69-8; L-Tryptophan Benzyl Ester

相似化合物

35858-81-2 22839-16-3 69876-37-5

上下游产品

CAS号69876-37-5 Cbz-L-色氨酸苄酯 | CAS号85612-31-3 benzyl 3-(1H-in...

📜N-叔丁氧羰基-L-色氨酸置于三乙胺,三氟乙酸体系中,用 乙酸乙酯,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 8.0H,反应生成 L-色氨酸苯甲酯
参考文献:Application Of A Unique Automated Synthesis System For Solution-Phase Peptide Synthesis.
标题:Application Of A Unique Automated Synthesis System For Solution-Phase Peptide Synthesis.
摘要:使用了一种适合于采用相似反应程序进行重复合成的自动化合成系统,系统性地合成了由5种保护氨基酸组成的所有可能的二肽(25种)和三肽(125种)库.该装置还被应用于10种激素pacap-27成分片段三肽衍生物的自动化合成.实验测得125种三肽库的分光旋转值与通过各成分氨基酸的分光旋转值总和计算得到的值相关性非常好.
DOI:10.1248/cpb.43.1272

专利信息

专利号:US-3953416-A
优先权日:1971-12-20
标 题:Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same
发明人：FOLKERS KARL; CURRIE BRUCE L; CHANG JAW-KANG; SIEVERTSSON HANS; BOGENTOFT CONNY
权利人:FOLKERS KARL; CURRIE BRUCE L; CHANG JAW KANG; SIEVERTSSON HANS; BOGENTOFT CONNY
摘要:A synthetic decapeptide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide which has the hormonal activities of the luteinizing hormone releasing hormone (LRH) of the hypothalamus gland of mammals is produced by utilizing as the key starting materials, the amino acids, glutamic acid or pyroglutamic acid, histidine, tryptophan, serine, tyrosine, glycine, leucine, arginine, and proline. Synthesis of the decapeptide is accomplished by coupling, in appropriate combinations of appropriate protected forms of the amino acids, and finally deprotecting to yield the amide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide.

专利号:US-4416820-A
优先权日:1981-01-14
标题:Indole derivatives and a method for production of peptides
发明人：FUKUDA TSUNEHIKO; KOBAYASHI SHIGERU; FUJINO MASAHIKO
权利人:TAKEDA CHEMICAL INDUSTRIES LTD
摘要:An indole group in an amino acid or a peptide can be protected with a group shown by the formula: wherein R1 and R5 each is hydrogen, methyl or methoxy; R2 and R4 each is hydrogen or methyl; and R3 is methyl or methoxy, and said group may easily be removed without affecting the amino acid or the peptide to be derived from the protected amino acid or peptide. Thus, the present invention is useful in the synthesis of a peptide containing an indole group.

专利号:US-2006079497-A1
优先权日:2004-10-12
标题:Lavendamycin analogues and methods of synthesizing and using lavendamycin analogues
发明人：BEHFOROUZ MOHAMMAD; BEHFOROUZ NANCY C
权利人:BALL STATE UNIVERSITY
摘要:Lavendamycin analogues, methods for their synthesis, and methods for their use in the treatment of diseases such as cancer and HIV infection are described.

专利号:KR-102204781-B1
优先权日:2013-06-05
标 题 :New compounds having triple activities of thrombolysis, antithrombotic and radical scavenging, and synthesis, nano-structure and use thereof

专利号:CN-113754675-B
优先权日:2020-06-04
标 题 :Synthesis, Biological Activity and Application of Dimethyldioxane-tetrahydro-β-carboline-3-carboxylic acid

专利号:CN-109912693-A
优先权日:2017-12-12
标题:Seven ring aldehyde of RGDS modification, synthesis, anti-thrombus activity and application