CAS: 40894-00-6; 3-Bromo-2,2-Dimethyl-1-Propanol

相似化合物

2843-17-6 1522-92-5 98244-48-5

上下游产品

5.5-dimethyl-1,3,2-dioxathiane-2-oxide diethyl ether acetic acid (3-bromo-2,2-dimethyl-1-propyl)ester 2,2-Dimethyl-1,3-propanediol 2,2-dimethyl-propanol-1 dipropyl-(3-hydroxy-2.2-dimethyl-propyl)-amine 3-(dimethylamino)-2,2-dimethylpropan-1-ol 3-diethylamino-2,2-dimethylpropanol

2,2-二甲基-1,3-丙二醇置于氢溴酸,溶剂黄146体系中,化学反应 12.0H,以45%的收率获得产物3-溴-2,2-二甲基-1-丙醇
参考文献:Tyrosine Kinase Inhibitors
标题:Tyrosine Kinase Inhibitors
摘要:本公开提供了诸如吡唑嘧啶化合物以及药学上可接受的盐,这些化合物是酪氨酸激酶抑制剂,特别是blk,Bmx,Egfr,Her2,Her4,Itk,Tec,Btk和txk,因此可用于治疗可通过抑制酪氨酸激酶治疗的疾病,例如癌症和炎症性疾病如关节炎等.还提供了含有此类化合物以及药学上可接受的盐的药物组合物,以及制备此类化合物和药学上可接受的盐的方法.

专利信息

专利号:US-5637757-A
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds
发明人：HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
权利人:GREAT LAKES CHEMICAL CORP
摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

专利号:US-5663449-A
优先权日:1989-05-19
标 题 :Intermediate compounds in the synthesis of heteroarylpiperidines, pyrrolidines and piperazines

专利号:WO-9632368-A1
优先权日:1995-04-11
标题:One-pot synthesis of ring-brominated benzoate compounds

专利号:EP-0825974-A1
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds

专利号:RU-2036924-C1
优先权日:1989-01-31
标题:Method of synthesis of imidazo-(1,2-b)-pyridazine or their salts and imidazo-(1,2-b)-pyridazine derivatives or their salts

专利号:CA-2217760-A1
优先权日:1995-04-11
标题:One-pot synthesis of ring-brominated benzoate compounds